A0A3P8U3K8 · A0A3P8U3K8_AMPPE

Function

Catalytic activity

Features

Showing features for binding site.

1835100200300400500600700800
TypeIDPosition(s)Description
Binding site41ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcentriole
Cellular Componentcentrosome
Cellular Componentcytoplasm
Cellular Componentkinetochore
Cellular Componentnucleus
Cellular Componentspindle pole
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Biological Processmitotic spindle organization
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase PLK4
  • EC number
  • Alternative names
    • Polo-like kinase 4
    • Serine/threonine-protein kinase SAK

Organism names

Accessions

  • Primary accession
    A0A3P8U3K8

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain12-265Protein kinase
Region316-438Disordered
Compositional bias343-360Basic and acidic residues
Compositional bias377-394Polar residues
Domain456-569Cryptic POLO box 1 (CPB1)
Domain570-684Cryptic POLO box 2 (CPB2)
Region678-701Disordered
Domain736-825POLO box

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    835
  • Mass (Da)
    92,699
  • Last updated
    2019-02-13 v1
  • Checksum
    83DD15B180783759
MSVSIGDKIEDFKVLTLLGKGSFACVYRAKSVKTGLEVAIKTIDKKAMHKAGMVQRVTNEVEIHCRLKHPSILELYNYFEDSNYVYLVLEMCHNGEMSRYLKERKMPFSEDEARHFMHQIVKGMLYLHTHGILHRDLTLSNLLLTSNMNIKVADFGLATRLKLPNEKHFTMCGTPNYISPEVATRSAHGLESDVWSLGCMFYAFLMGRPPFDTDTVKHTLSKVVLGEYEMPTHVSLEAQDLIHQLLQKDPAQRPSLSAVLDHPFMTQSLLVRTKELGLEDDGSIDSGIATISTACTSSTSASSGSRLQRRTRHMIGSALPNRMTPIPSLPRQTNSGCFEDGDLWRQPADRFNREGRSRAVHVGESGQPHSRYLRRAYSSDRSSSTASGQSSGHAELGRCHSEETLAGVGRPVFPTSSTPNPFSEHGRHPSPPFETPHVRELQLPSAKPTAEKQKKTLKDIVPPLCASRLKPIRQKTKNAVVSILDTGEVCMELLKCQNGQERVREVLRISCDGSMVTIYQPNGGKGFPVLDCPPAPPEDILICSYEDLPEKYWKKYQYASRFVQLVKSKTPKVTLYTKYAKVMLMENTPSADLEVCFYDGAKTHKTSELVRVVEKSGKSYTVKGEVGLSGLSPESRQYVELSDEGHSMCLALEAAITAEEQRSTNSVPFFPITIGRYDENSSQPSHPVPPDAASPPKPPQITPSMISYDGSDFTTASLSKKSSPVRQDLVQSTGKVVKSIFVPNVGWASQLTSGEVWVQFNDGSQLVVQAGVSCITYTSPEGRITSFVKLAPLSEQEKYKENEKLPEHVKEKLHCLSTILGLLANPAAHHRQHSH

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3P8U8L8A0A3P8U8L8_AMPPE926
A0A3P8U6Z6A0A3P8U6Z6_AMPPE903
A0A3P8UCW7A0A3P8UCW7_AMPPE97

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias343-360Basic and acidic residues
Compositional bias377-394Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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