A0A3P8U3K8 · A0A3P8U3K8_AMPPE
- ProteinSerine/threonine-protein kinase PLK4
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids835 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 41 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | centriole | |
Cellular Component | centrosome | |
Cellular Component | cytoplasm | |
Cellular Component | kinetochore | |
Cellular Component | nucleus | |
Cellular Component | spindle pole | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase PLK4
- EC number
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Pomacentridae > Amphiprion
Accessions
- Primary accessionA0A3P8U3K8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 12-265 | Protein kinase | |||
Region | 316-438 | Disordered | |||
Compositional bias | 343-360 | Basic and acidic residues | |||
Compositional bias | 377-394 | Polar residues | |||
Domain | 456-569 | Cryptic POLO box 1 (CPB1) | |||
Domain | 570-684 | Cryptic POLO box 2 (CPB2) | |||
Region | 678-701 | Disordered | |||
Domain | 736-825 | POLO box | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length835
- Mass (Da)92,699
- Last updated2019-02-13 v1
- Checksum83DD15B180783759
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A3P8U8L8 | A0A3P8U8L8_AMPPE | 926 | |||
A0A3P8U6Z6 | A0A3P8U6Z6_AMPPE | 903 | |||
A0A3P8UCW7 | A0A3P8UCW7_AMPPE | 97 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 343-360 | Basic and acidic residues | |||
Compositional bias | 377-394 | Polar residues | |||
Keywords
- Technical term