A0A3P8RYI8 · A0A3P8RYI8_AMPPE

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentextracellular region
Cellular ComponentGolgi apparatus
Cellular Componentlysosome
Cellular Componentmitochondrial outer membrane
Cellular Componentvacuolar membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionheme binding
Biological Processiris morphogenesis
Biological Processmelanocyte proliferation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Organism names

Accessions

  • Primary accession
    A0A3P8RYI8

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein
Mitochondrion outer membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane27-50Helical
Transmembrane87-103Helical
Transmembrane124-142Helical
Transmembrane162-180Helical
Transmembrane243-266Helical
Transmembrane363-386Helical
Transmembrane392-412Helical
Transmembrane483-500Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain246-529ABC transmembrane type-1
Domain563-797ABC transporter
Region797-832Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    832
  • Mass (Da)
    95,567
  • Last updated
    2019-02-13 v1
  • Checksum
    915C2EA9B613D019
MGFIHSYCEANSSISHTWLDEGISPCFYFTLVPTTLLTIAFFLGTIHWIFYQKYGTAMEPKFIPRSRLYGFQQALSIILLLQELPGYVVLYGCFSILGWAWAVSTLRVERRRVLIMDRTRGHSAVLLLFWAVAFSAENLAFVSWYSPHWWWNLENNQQQVQFALWLMRYIATGLLFFIGLKAPGLPRRPYMLLINEDERDVENSRQSLLGRTEENESTWRGFWKKVRLLVPYMWPRGNVFLQLLVLFCLGLLGVERAINVFVPIYYKNIVNELTDGSSWHTLATTVCIYVLLKFMQGGGAGASGFVSNMRSFFWIRVQQYTNRVVQVRLFSHLHSLSLRWHLGRKTGDVLRSIDRGTSSINSLLSYIVFSIFPTIADIVISIIYFITYFNAWFGLIVFICMALYLTLTIIITEWRTKYRRDMNLQDNNAKSKAVDSLLNFETVKYYNAENYEVSRFEDAILKYQASEWKTQASLAFLNQTQNLIIGSGLLAGSLLCAYFVGDFVLFGTYIIQLYTPLNWFGTYYRMIQNSFIDMESMFKLFEEEEEVKDEVNAGNLLYKLGKVEFENVYFSYTNGKEILKDVSFTVLPGQTVALCYYHYFLLIPHRWDLRDPGKSTIIRLLFRFYNFVVFPQVKQTSLRAHIGVVPQDTVLFNDTIRDNIRYGRISASDQEVEEAALAADIHDKIMEGYDTQVGERGLKLSGGEKQRVAIARTILKAPQIILLDEATSALDTQTERNIQASLAKVCANRTTIVVAHRLSTIIGADQILVINDGRIAERGQHDELLLKGGLYAEMWLNQQQAQDSDSSSETESKDRKSEKLQPPSTSAGHQGD

Keywords

Genome annotation databases

Similar Proteins

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