A0A3P8RQC8 · A0A3P8RQC8_AMPPE

Function

Catalytic activity

Features

Showing features for binding site, active site.

114592004006008001,0001,2001,400
Type
IDPosition(s)Description
Binding site397-405ATP (UniProtKB | ChEBI)
Binding site420ATP (UniProtKB | ChEBI)
Active site655Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functioneukaryotic translation initiation factor 2alpha kinase activity
Molecular Functionhistone H2AS1 kinase activity
Biological ProcessDNA damage checkpoint signaling

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      EIF2AK4

Organism names

Accessions

  • Primary accession
    A0A3P8RQC8

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-67Disordered
Compositional bias49-64Basic and acidic residues
Domain94-338Protein kinase
Domain391-810Protein kinase
Region464-548Disordered
Compositional bias475-498Basic and acidic residues
Compositional bias512-531Polar residues
Region561-593Disordered
Region1316-1344Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,459
  • Mass (Da)
    164,543
  • Last updated
    2019-02-13 v1
  • Checksum
    ADCBD1A463B5B75F
MAKQELRESMEQSVSVLGKSPPSPGGATPELIEARKAAGNRRRTTSNTRHRRDTNNEDNHRSQEPLHFNSSTFGELLVHRGKSLGASERLNRNVYYGFEAISGEFAVIYEWSLRWNKKMGKFFTTQEKGKIENCKKQIHGAENEFNSLLRLDHPNLVHYMALSSTEKEDCLVVNLLVEHVAGINLNQSLNTHTPVPLDKLCHYTAQLLAALDYLHSNSVVHKQLGPSSVLVDSEGRIRLTDYSLSKRFADICKEDIFEQAHVRFSEDTAMPTKTGKKGDVWNLGLMLLALSQGKEAKEYPVTVPASLPADFQDFLHKCVCLNDAERWTTQQLLEHSFLKPPSPKNLLQYQDNSPEDLAVDFASSVIPRSHILNAPFSSGLQGQLSRYFNEFEELQLLGKGAFGAVIKVQNKLDGCYYAVKRIQVNPACKQFRRIKGEVTLLSRLNHENIVRYYNAWIERHETPSTGVLSNTDSSEPRSTDEKSPQCRDPPHHINELGLPDNVEDIAPPPALSSSVEWSTSIERSSSAKCSGHQSSDDEDDDDDDDEDVFCASFLPLDSDSRSDIIFDNGDESIDEMSQVEPSKRPVTDTTESTDSDRNLLIAHYLYIQMEYCEKSTLRDTIDHGLHQDQNRLWRLFREILDGLAYIHEQGMIHRDLKPVNIFLDSQDHVKIGDFGLATDHPANVAAGKLEVEENSSAVMLKPDPTGNMTGMVGTALYVSPEVQGNTKATYNQKVDLFSLGIILFEMSYRPMTTGAERITVLSQLRVEPMCFPEDFTPCEQGTQRKVIEWLLKHDPALRPTAQELLKSDLLPPPQMEESELHEVLQHTMANVNGKAYRTMVGQLFAQNTSPVMDFTYDIDMYKGSFSFNGAKLQQHVYETITRIFKKHGAVRLQTPLLLPRNRKLYDGSELACFMDHSGMLVTLPYDLRMAFSRYVARNNIMHLKRYSIERVFRPRKLDRAHPRELLECAFDIITPVTNSLLPDAETIYTISEIVQEFPALQERNYNIYLNHTSLLKAILLHSGVPEDKLSQASNILCDAMSEKLTKREVEAKFCNFSLSTNSLQTLYKYIEQKGNLQDLAPLLASLTKQKMAVTQLAKQGLKDLEELTVLLHRLGVKLRVVVNLGLVYKVQHHSGVIFQFVAFIRKRKRTVPDIVAAGGRYDHLILEFRGPASTVPVPSAVGASIALDKVCAAMASMEEPPTVSSCDALVVPVGHSAMSRAINVVQKLWSTGVSADIAYDVSQSQEALLEHCRLAGITCMALVSDKEGNYVKVKSFEKDRQSEKRIPESDLVDHIIQKCRTKFSDERNIREISETMTLQNPKGSQLNNTGSSEQHGSGSTTNMNVNVISPEKVSASARRRYETQIQTRLQNFGSNLQNKSNDIEVLAVDLQKETLINFLSLEFDSEEQFNGSVKTLLSRLPKQRYLKSICEEIHHFKIAKRVAVVVLYSYKDDYYKVLM

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3P8RLV2A0A3P8RLV2_AMPPEEIF2AK41396

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias49-64Basic and acidic residues
Compositional bias475-498Basic and acidic residues
Compositional bias512-531Polar residues

Keywords

Genome annotation databases

Similar Proteins

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