A0A3P2RDD6 · A0A3P2RDD6_WEIVI

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site76Na+ (UniProtKB | ChEBI); structural
Binding site79Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • ORF names
      D3P96_08170

Organism names

Accessions

  • Primary accession
    A0A3P2RDD6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane34-57Helical
Transmembrane64-85Helical
Transmembrane97-115Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    126
  • Mass (Da)
    13,627
  • Last updated
    2019-02-13 v1
  • Checksum
    A38135A156E90EE8
MMRYWQRILAVASGGFIGGGTREGLELLFNGPNFPIGTLFINLSGTMLSVVAVVIFIDKFTVDPLIFDFISVGILGAYTTYATLITETMTKLSPLVGLGYITLSIVGSVLMVYLGRYAARKVVHLA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RHGY01000012
EMBL· GenBank· DDBJ
RRG17375.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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