A0A3P2A087 · A0A3P2A087_9BACT

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site505Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      EII23_00530

Organism names

  • Taxonomic identifier
  • Strain
    • OH1186_COT-070
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Desulfovibrio

Accessions

  • Primary accession
    A0A3P2A087

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue106N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain81-348Orn/DAP/Arg decarboxylase 2 N-terminal
Domain374-453Arginine decarboxylase helical bundle
Domain583-636Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    638
  • Mass (Da)
    71,906
  • Last updated
    2019-02-13 v1
  • Checksum
    B30DEF06BA29DFE2
MARNRALQQWRVEDSVELYGINSWGAGYFDVSDKGDVVICPHGPRGPQVSIPEIIAGLHERGYDMPVLLRVENILDARIANIHDSFRKAIKNLNYTGSYRGVFPVKVNQQQQVVEKITQFGAKYHHGLEVGSKAELIAAISLMTDRKACVICNGYKDEEFIDLGLQALRLGFNVFFVLEMPSELEVVLERSKALGVRPNIGVRAKLSSKVGGHWTDSGGDRSTFGLSPAQIVDVVDTLKASDMLDCFQLLHYHLGSQVSNIRDIRTGVMEGARLYVGLVQEGAPMGYLDLGGGLAVDYDGTHTNYISSRNYSLDEYCTDVVEAVMSILDEQGVPHPHIITESGRATVAYYSVLLFNILDVSVVEEVHLPESLPEDSPEPVRNLRETLAGISLRNLQECYNDAIYYRDEMRQMFFAGRVTLRQRTLAERFFWAIIMRIAQEKTRLKNVPRDLADIDVSLADIYYGNFSVFQSLPDSWAIDQIFPIMPVHRLKEFPSRQAIISDITCDSDGRIDHFIDPQGVKPTLDLHPLRDGEEYYLGVFLVGAYQETLGDLHNLMGDTNVVSIRVAEDGTYEYTREIRGDSVADILSYVEYEPRRILEDLRSTAEQAVRQGRISPSERFAIMQAFEDGLRGYTYFER

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RQYH01000001
EMBL· GenBank· DDBJ
RRD88498.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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