A0A3P1WGV4 · A0A3P1WGV4_9ACTN

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site189Tele-phosphohistidine intermediate
Binding site289phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site325phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site414Mg2+ (UniProtKB | ChEBI)
Binding site437-438phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site438Mg2+ (UniProtKB | ChEBI)
Binding site448phosphoenolpyruvate (UniProtKB | ChEBI)
Active site485Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsP
    • ORF names
      EII42_09810

Organism names

  • Taxonomic identifier
  • Strain
    • OH4464_COT-324
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Propionibacteriaceae > Tessaracoccus

Accessions

  • Primary accession
    A0A3P1WGV4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-126Phosphotransferase system enzyme I N-terminal
Domain153-224PEP-utilising enzyme mobile
Domain251-520PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    560
  • Mass (Da)
    57,869
  • Last updated
    2019-02-13 v1
  • MD5 Checksum
    7B4D61A87D7B149C59612DE92A61C195
MTARLKVRTFTGIGVSPGGVSAPVVVVLPPEPLPDETCSLDHHEAAARVAQALAEVGDELEARAATLGEDARQMLTAAALMARDEGLLDAAHEQLRAGLGPAHAIQAAVASYSAELKELGGYFAERVSDLNDVGQRAIARVLGRPAPGLPKLNQPCIVVAEDLAPADTATLDPSLVVGLVTSGGGITSHTAILAAQRGIPAVVQAAGVLELSSGTIVALDGDTGRVVAEPDEAVIAGLERRRRARERIDASGPGHTADGYPVALLANIGGPEEARAAARLDVEGVGLFRTEFVFLTATSAPTLEQQTRLYREVLEPFGQRPVTVRALDAGADKPLPFANLGEEPNPALGRRGLRLMKERTELLEVQLAALAAAQRSCEAQVKVMAPMVATLAEAEWFTAAAHAVGLETAGIMIEVPAAALSAEHLLQVSDFASVGTNDLAQYTMAADRMLGQLSELLDPFQPAILRLVGLACAAGHSTGKPVGICGESAADPLMALVLAGLGATSLSMPASRVPLVRHALSLHTLACCQEMAQAAAGARNALDARSAVAALADERLTSLL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RQYZ01000019
EMBL· GenBank· DDBJ
RRD45824.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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