A0A3N5R9D8 · A0A3N5R9D8_UNCCH

Function

function

Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    EC:2.7.13.3 (UniProtKB | ENZYME | Rhea)

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular Functionphosphorelay sensor kinase activity
Molecular Functionprotein dimerization activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Oxygen sensor histidine kinase NreB
  • EC number
  • Alternative names
    • Nitrogen regulation protein B

Gene names

    • ORF names
      EHM41_19380

Organism names

Accessions

  • Primary accession
    A0A3N5R9D8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-199Histidine kinase

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    199
  • Mass (Da)
    22,045
  • Last updated
    2019-02-13 v1
  • Checksum
    A6D37F3DCFA1A38D
LSRELHDQTAQDITTLSLGLKTIEDSNLERESLKEEIQKLQKITSILGHKIHQIAFELRPSSIDDLGLLQTLQSYTFEWSKENGIPVELETISSDKTDIPLSTSINVFRIVQEAFNNILKHAQATRVSLIYEQKPEIIKIVLEDDGIGVHLEQITSANSGKQLGLLGMKERAEIAGGTLTIESGQNKGTTVFLSIPLGQ

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RPPQ01000510
EMBL· GenBank· DDBJ
RPI82032.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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