A0A3N2BYD4 · A0A3N2BYD4_9MICO
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids123 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 74 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 77 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Plantibacter
Accessions
- Primary accessionA0A3N2BYD4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 33-53 | Helical | |||
Transmembrane | 60-79 | Helical | |||
Transmembrane | 99-122 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Sequence similarities
Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length123
- Mass (Da)12,014
- Last updated2019-04-10 v1
- MD5 ChecksumD46FF18B438724E5567A9F3168E1FC79
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
RKHL01000001 EMBL· GenBank· DDBJ | ROR80266.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RKHL01000001 EMBL· GenBank· DDBJ | ROR83228.1 EMBL· GenBank· DDBJ | Genomic DNA |