A0A3M8EZY7 · A0A3M8EZY7_DESBX

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site282-292substrate
Active site502Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processputrescine biosynthetic process from arginine
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      ED859_04555

Organism names

Accessions

  • Primary accession
    A0A3M8EZY7

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue100N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain75-342Orn/DAP/Arg decarboxylase 2 N-terminal
Domain372-449Arginine decarboxylase helical bundle
Domain584-633Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    635
  • Mass (Da)
    71,765
  • Last updated
    2019-02-13 v1
  • Checksum
    97EB0AF4C557BA6B
MERWSINESAKVYNINNWGADLFSINKKGNVCVHPSPTSKHSIDLRALVDDLIKRKIKPPILLRFMDILQGRIASINRVFKNAIEENDYPAKYQTFYPIKVNQQRQVVEAIAKFGKRYNIGLEVGSKPELVIGLSFATGNGIPIICNGYKDNEYIETVLYATKIGYDITIVVEKMFELEKIIALSKKTGIRPKLGIRVKLSSKGTGKWATSGGEDAKFGLRMSEIIAAINVLQRNDLLDNVKLLHFHIGSQITKIDKIKTALIEGTRIYTEMKKLGVGIEFLDIGGGLGVDYDGSKSSYFSSVNYSIEEYANDVIYQIKNICDDAGVECPNIISESGRATVAHYSVLVTNALNTNTQNLMPDFEETLNGTEKLAPTVKKLVDIYKSIDRYSLREDYHDTVQLINEAVSLFNLGYLTLSERAMAEWLHGKILRKINGIVEKIKPIPEELQNFQLSLRQTYFANFSLFQSIPDSWAIDQLFPIVPIQRLNQKPDVMASVADITCDSDGEITSFVGENGRTKYLPLHRIRKDEDYFIGFFLIGAYQEILGDMHNLFGDTNAVHVTFNKKTGYKIDTVINGDATWESLKYVQYKGPEILKHVRDNLEKDVALRKISIEESSHFLELLDRTLLGYTYLGE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RHLS01000005
EMBL· GenBank· DDBJ
RNC71427.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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