A0A3M7MI08 · A0A3M7MI08_9PLEO

Function

function

Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleolus
Cellular ComponentP-body
Cellular Componentsno(s)RNA-containing ribonucleoprotein complex
Cellular Componentspliceosomal complex
Cellular ComponentU4/U6 x U5 tri-snRNP complex
Cellular ComponentU6 snRNP
Molecular FunctionRNA binding
Biological Processmaturation of SSU-rRNA
Biological ProcessmRNA splicing, via spliceosome
Biological ProcesstRNA processing

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    U6 snRNA-associated Sm-like protein LSm6

Gene names

    • ORF names
      GMOD_00004983

Organism names

  • Taxonomic identifier
  • Strain
    • CCB06
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Pleosporineae > Pleosporaceae > Pyrenophora

Accessions

  • Primary accession
    A0A3M7MI08

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain32-104Sm

Sequence similarities

Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    480
  • Mass (Da)
    52,074
  • Last updated
    2019-02-13 v1
  • Checksum
    D3D136E373AB7DE7
MLLCTYVPASTAVDMSTNGESPAPEAAADARDPSGFLSDIIGAPVTVKLNSGIIYKGDLQSVDGYMNIALERCTEVADGRVTRNWGDAFVRGNNVHTAMLDLGLIHLKGLGLSSHRNTVPVARPIHSRLPTHRHLILSLTMAVPKVKSRIQFQSRQKHGGPRNNKQRIAVAQSNQTSNTAHGSKEADEVGVAKRKWHASSKGESQLQRGYTLSGAIGRVLRAAALEPLLSSIAGVSNFIYSTVNQDYDPNDSLISQAPRLVPVPEENSQDAQELPLLLVAKAKTEASTTWHQWLVSLFAGRKAIPSARNGDRTEPSAALNSACQQQLQPAKGSEETTLVGVVSAPSAPRLTLQQATVRAKPSPCLSYREILPGRTTRYTGYAVVAPGEHQAAIVQRGFNVLGSQQQTPTASRRMNSANSLLDRGGDAWTVWSRTNPVMESKYFTRTRSDTPLLHPQSEATISKHFEQPKVKISKLRDTHI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KE747843
EMBL· GenBank· DDBJ
RMZ74130.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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