A0A3M0MRJ8 · A0A3M0MRJ8_9LACO

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site13ADP (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site13sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site17ADP (UniProtKB | ChEBI)
Binding site83glycerol (UniProtKB | ChEBI)
Binding site83sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site84glycerol (UniProtKB | ChEBI)
Binding site84sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site135glycerol (UniProtKB | ChEBI)
Binding site135sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site245glycerol (UniProtKB | ChEBI)
Binding site245sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site246glycerol (UniProtKB | ChEBI)
Binding site267ADP (UniProtKB | ChEBI)
Binding site267ATP (UniProtKB | ChEBI)
Binding site310ADP (UniProtKB | ChEBI)
Binding site310ATP (UniProtKB | ChEBI)
Binding site314ATP (UniProtKB | ChEBI)
Binding site411ADP (UniProtKB | ChEBI)
Binding site411ATP (UniProtKB | ChEBI)
Binding site415ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      F5ESL0233_07495

Organism names

  • Taxonomic identifier
  • Strain
    • ESL0233
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus

Accessions

  • Primary accession
    A0A3M0MRJ8

Proteomes

Subcellular Location

Interaction

Subunit

Homotetramer and homodimer (in equilibrium).

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-252Carbohydrate kinase FGGY N-terminal
Domain262-450Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    505
  • Mass (Da)
    56,075
  • Last updated
    2019-02-13 v1
  • Checksum
    86D489AB70389D88
MAKNYIMAIDEGTTSTRAMIIDHQGRKVASSQKEFPQYFPQPGWVEHKAEEIWHAVQTTIANAIINSGIRPEQIKGIGITNQRETTVIWDKKTGKPIYNAIVWQSRQTTKLAEKLKNAGYSKLIHKKTGLIIDPYFSATKIRWILDNVAGAQQKAEQGDLLFGTIDSWLLWKLTDGAVHVTDYTNASRTMLFNIHDLKWDEDILELLNIPKKMLPEVKSNSEIYGYTNSYTFFGGKVPICGIAGDQQAALFGQLALKKGMVKNTYGTGSFIVMNTGEEPTESDNNLLTTIAYGLNGQINYALEGSIFVSGSAIQWLRDSMKMVKTATESETAAKLSKSENEVYVVPAFTGLGAPYWDSAARGAVFGVTRGTNRNDFIKATLQSLAYQTRDVVDTMQIDSGIKIPTLRVDGGASNNDYLLQFQADLLGIKIERAQTLETTALGAAFLAGLAVGYWKDLDELKDIFVVGKTFECQMAEEERNRLYQGWKRAVKATQVFAHGEEALNK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
REHH01000009
EMBL· GenBank· DDBJ
RMC40259.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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