A0A3M0LVB4 · A0A3M0LVB4_9LACO

Function

function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.
    EC:7.4.2.8 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

1799100200300400500600700
TypeIDPosition(s)Description
Binding site85ATP (UniProtKB | ChEBI)
Binding site103-107ATP (UniProtKB | ChEBI)
Binding site504ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell envelope Sec protein transport complex
Cellular Componentcytosol
Cellular Componentplasma membrane
Molecular FunctionATP binding
Biological Processintracellular protein transmembrane transport
Biological Processprotein import
Biological Processprotein targeting
Biological Processprotein transport by the Sec complex

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein translocase subunit SecA
  • EC number

Gene names

    • Name
      secA
    • ORF names
      F5ESL0246_02645

Organism names

  • Taxonomic identifier
  • Strain
    • ESL0246
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus

Accessions

  • Primary accession
    A0A3M0LVB4

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cytoplasm
Membrane
; Peripheral membrane protein
Note: Distribution is 50-50.

Keywords

Interaction

Subunit

Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

Family & Domains

Features

Showing features for domain, coiled coil.

Type
IDPosition(s)Description
Domain1-582SecA family profile
Coiled coil2-39
Domain87-245Helicase ATP-binding
Domain426-599Helicase C-terminal

Sequence similarities

Belongs to the SecA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    799
  • Mass (Da)
    91,381
  • Last updated
    2019-02-13 v1
  • MD5 Checksum
    B00D7502C5753FCF19720C2446B4467F
MVNVLKKLYNNDKRELKKFEKLANQVENYADEYDKLSDEELKAKTPEFRARLEKGEELDKILPEAFGVAREGAKRVLGLYPFHVQILGGIALHFGNIAEMMTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSSRDAEEMGQLYKWLGLTVGLNLNSMSPDEKREAYDCDVTYSTNAELGFDYLRDNMVVYKEQMVQRELNYAIIDEVDSILIDEARTPLIISGEAEQANGDYIRADRFVKSLHEDTSGDDADDDEDHGDYKIDWPTKSIALTRTGIQKACDHFGLKNLYDVENQKLVHHLDQALRANYIMLNDIDYVVQDGEVLIVDSFTGRVMSGRRYSDGLHQAIEAKEGVKIQEESKTQATITYQNFFRMYKKLSGMTGTAKTEEEEFREIYNMQVITIPTNRPNIRKDQSDILYPTLNSKFEAVVNEIKERHSKGQPVLVGTVAVESSERLSKMLNQAGIPHAVLNAKNHAKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGVTRFYLSLEDDLMKRFGGDRVKDFLDRLSDNDDDKVIESRLITRQVESAQKRVEGNNYDTRKQTLQYDDVMRIQREIIYGERMQVIGEETSLKDVLIPMIHRTINSQVDMFTQGDRSKWRLDSLRDFISSSLTNDEEVEKLDFKTITVPELKQKLYEFVEENYQQKKQILADPSDMLEFEKVVILRVVDDRWTDHIDAMDQLRQSISLRGYGQLNPLVEYQDSGYNMFEEMISNIEFDVTRLFMKAEIRQNLSR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
REHC01000006
EMBL· GenBank· DDBJ
RMC29141.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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