A0A3L6TDS4 · A0A3L6TDS4_PANMI

Function

function

Bifunctional aspartate kinase and homoserine dehydrogenase that catalyzes the first and the third steps toward the synthesis of lysine, methionine and threonine from aspartate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a metal cation (UniProtKB | Rhea| CHEBI:25213 )

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.

GO annotations

AspectTerm
Molecular Functionaspartate kinase activity
Molecular FunctionATP binding
Molecular Functionhomoserine dehydrogenase activity
Molecular Functionmetal ion binding
Molecular FunctionNADP binding
Biological Processhomoserine biosynthetic process
Biological Processlysine biosynthetic process via diaminopimelate
Biological Processmethionine biosynthetic process
Biological Processphosphorylation
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

    • UPA00034UER00015
    • UPA00050UER00063
    • UPA00051UER00462

Names & Taxonomy

Protein names

  • Submitted names
    • Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic isoform X1

Gene names

    • ORF names
      C2845_PM03G30710

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Panicodae > Paniceae > Panicinae > Panicum

Accessions

  • Primary accession
    A0A3L6TDS4

Proteomes

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region15-40Disordered
Compositional bias25-40Polar residues
Domain391-466ACT
Domain472-549ACT

Sequence similarities

In the C-terminal section; belongs to the homoserine dehydrogenase family.
In the N-terminal section; belongs to the aspartokinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    895
  • Mass (Da)
    96,885
  • Last updated
    2019-02-13 v1
  • Checksum
    9894924B77A6E6F0
MRGLAVASPLPPAATAARRWPRASSSARIGQSQGSLHKHHSTNLLRPAAAAISVKQDEVNTYLPKGDMWSVHKFGGTCMGTPQRIQSVADIVLGDSSERKLVIVSAMSKVTDMMYNLVHKAQSRDDSYMIALEEVFEKHMAAAKDLLDGEDLARFLSQLHSDVSNLRAMLSAIYIAGHATESFSDFVVGHGELWSAQMLSYAIKKSGAPCSWMDTREVLVVKPSGSNQVDPDYLESEKRLQKWFSRQPAEIIVATGFIASTAENIPTTLKRDGSDFSAAIIGSLVRARQVTIWTDVDGVFSADPRKVSEAVILSTLSYQEAWEMSYFGANVLHPRTIIPVMKDNIPIVIRNMFNISAPGTMICRQPANDNGDLDACVKSFATIDNLALVNVEGTGMAGVPGTSSAIFSAVKDVGANVIMISQASSEHSICFAVPEKEVAAVSAALHVKFREALAAGRLSKVEVIKGCSILAAVGLRMASTPGVSAMLFDALAKANINVRAIAQGCSEYNITVVLKQEDCVRALRAAHSRFFLSTTTLAVGIIGPGLIGGTLLNQLKDQAAVLKENMNIDLRVIGITGSSTMLLSDTGIDLTQWKELLRKEAEPADLANLVRHMSDNHVFPNKVLVDCTADTSIASHYYDWLKKGIHVITPNKKANSGPLDRYLKLRTLQRASYTHYFYEATVGAGLPIISTLRGLLETGDKILRIEGIFSGTLSYIFNNFEGTRTFSDVVAEAKEAGYTEPDPRDDLSGTDVARKVIILARESGLRLELSDIPVKSLVPEALASCSSADEFMQKLPSFDQDWAKQRSEAEAAGEVLRYVGVVDAVNQKGQVELRRYKRDHPFAQLSGSDNIIAFTTSRYKEQPLIVRGPGAGAEVTAGGVFCDILRLASSLGAPS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias25-40Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PQIB02000002
EMBL· GenBank· DDBJ
RLN34986.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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