A0A3G8GL65 · A0A3G8GL65_9BURK

  • Protein
    Nucleoside diphosphate kinase
  • Gene
    ndk
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site11ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site87ATP (UniProtKB | ChEBI)
Binding site93ATP (UniProtKB | ChEBI)
Binding site104ATP (UniProtKB | ChEBI)
Binding site114ATP (UniProtKB | ChEBI)
Active site117Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDK
    ; NDP kinase
  • Alternative names
    • Nucleoside-2-P kinase

Gene names

    • Name
      ndk
    • ORF names
      EGT29_13390

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • H8
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Alcaligenaceae > Pigmentiphaga

Accessions

  • Primary accession
    A0A3G8GL65

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-140Nucleoside diphosphate kinase-like

Sequence similarities

Belongs to the NDK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    141
  • Mass (Da)
    15,455
  • Last updated
    2019-02-13 v1
  • Checksum
    C94184DADDAE8DE4
MAIERTLSIIKPDAVSKNVIGQIVSRFEAAGLKVIAARMMQLSRSDAERFYAVHAARPFFKDLVDFMVSGPVFVQVLEGESAIQKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAVETAKVEVAFFFPELNIHSR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP033966
EMBL· GenBank· DDBJ
AZG08779.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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