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A0A3G8GE08 · A0A3G8GE08_HUMAN

  • Protein
    ABO antigen
  • Gene
    ABO
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Features

Showing features for binding site, active site.

135450100150200250300350
Type
IDPosition(s)Description
Binding site121-123UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site126UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site211Mn2+ (UniProtKB | ChEBI)
Binding site211-213UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site213Mn2+ (UniProtKB | ChEBI)
Binding site233an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Binding site245an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Active site303Nucleophile
Binding site303an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Binding site326an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionhexosyltransferase activity
Molecular Functionmetal ion binding
Biological Processcarbohydrate metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ABO antigen
    • B-specific alpha 1->3 galactosyltransferase

Gene names

    • Name
      ABO

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A3G8GE08

Subcellular Location

Membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-37Helical

Keywords

  • Cellular component

PTM/Processing

Proteomic databases

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 6 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    354
  • Mass (Da)
    40,879
  • Last updated
    2019-02-13 v1
  • MD5 Checksum
    7242281E4253CEAB585E1923F5403974
MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDHLQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVGAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH137796
EMBL· GenBank· DDBJ
AZG06266.1
EMBL· GenBank· DDBJ
Genomic DNA
MK302441
EMBL· GenBank· DDBJ
QBZ81786.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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