A0A3G6VA63 · A0A3G6VA63_9RHAB

Function

Catalytic activity

  • GTP + H2O = GDP + phosphate + H+
  • a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
  • a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-homocysteine + H+
    EC:2.1.1.375 (UniProtKB | ENZYME | Rhea)
  • a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine + H+
  • a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H+ = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate
    EC:2.7.7.88 (UniProtKB | ENZYME | Rhea)

GO annotations

AspectTerm
Cellular Componentvirion component
Molecular FunctionATP binding
Molecular FunctionmRNA 5'-cap (guanine-N7-)-methyltransferase activity
Molecular FunctionRNA-dependent RNA polymerase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA-directed RNA polymerase
  • EC number
  • Alternative names
    • Replicase
    • Transcriptase

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • LS
    • TM
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae > Betarhabdovirinae > Cytorhabdovirus > Cytorhabdovirus oryzae

Accessions

  • Primary accession
    A0A3G6VA63

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain566-755RdRp catalytic

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,066
  • Mass (Da)
    235,786
  • Last updated
    2019-02-13 v1
  • Checksum
    57B96D212EBF02BD
MDLDDGGLWRRARGLGDYHLRSALVTPSLERFRSRKGRHREQLCFDRMKSLGWMLRWVDQGKLLGYLMVEANKSLPKSIANQELLVETLKLEYGCLRQIIMTDGDLHDQVISYLDRKSISTHYTHGREVFQEALIVVMALSSGREPPDHVNNLGYEMLNEELEVPVVRTYGVIFYLFGDLIYVKYPEEEGMITLDMFRNLTDKFSERENIMIATQLGTEILQEIYPSETVLKTVFSLWDKGLLKEGNDFYTVVKTFEAIINGMLIKNNDGTYYDPSAYLRETIMGLPVRLRDYAQTLVSYLDSLPFNPHHLSQIGGLFRLWGHPIVDPNAGVRKVRLLGTADKMNLTHIPTLAERKFKEIFYLSYYEKHRVYPNHNLNGEIEGSYLLSQLAQMALVNPKHANYSLVDWDSVNTLETFPFPKSFNLSLIIADKAVSPNREEWLELRRKGGTQMDPHIRRGPLKAMKDGVIDCEKLLRKINRNPSGLAKKHRIIGLYPKEREENMVPRMFALMSFDMRAFSVVSESMIADHIIPHIEGVTMTKSMLALQKEMIISTKSQASSTQSDSITFCLNIDFEKWNLNFRRWMTEGVFREMGRLFGLPEIFNRTYDIFKKSIIYLADGSFDLLLTDELEIEPGTNPDCAYTGHVGGFEGLRQKGWTVFTAVLISSICDEMGIKTHLMGQGDNQVLMLTIYSRAARETGDLKSAPAVLEITNTLETFKSRLVSLFANLGLPIKPLETWVSEELFAYGKTPIYRAVPLAMSLKRISRVFAFSNEDLMTLSNALGAISANAQAASMCDVHPMVSYAIAKWQHLCCAIIFSNYHPLCGCAPHVSGEEWAIKLRLPSGKKIQETSDEEIDERDLMKLIVTIPRSLGGYNTLTLYEMIMRGFSDPVSRDMCWLFAIASESTGKLRGYLINWIKPIVSPEVNAQHLIQDPTALNLLVPPNATSVIKRMIDKSLEALPKRSQFAVWFSEILEISGDKEISKLAEALTRTDSLNPRFLHDILGATLYGYCTAITSKVDKTVTLSRMALASKDVVGALIKGEMRLYSYFGWRTLQSRGLPLTTRCPNKWVRIIRDISWQKQIKAVSVPYPTHFLSEDISETDRPDSWIECYIDDAPTSDRSCMIYSTGKALPYLGSVTREKLTTRGAKAAYGTEPLVLRPINLVRTIGWFIEEDSNFAELIKMLLGAVTDLPIEEVLYIPEMVSGSMAHRYLDMSTQHGSLWMPLYGPATFLHMSTNTFVQYLKGTENVTLHFQCVMGLIQYAIVNKALGECPTKRMTRFFRSCPDCIVPIDDTLEDLPEVPSLDLIPERTTNPYLYLKKEKIELNVRHRLAVINEIRVIARDEIEETPLLANNTLEDVMSLRAAQRIFYTAKGKEAQWDLQTADREGYLKLDFVSVIRKIIGHLFVMESETLKAGSDYPTFQLQQRRIMRRVRQSDTSNFVHLGGFFCWQESIARIQKLKWSVMPATFPITAESVSLAAKMSLIGAMASGLTPKRCDGVLAENLIPDVTRQAKNIICLDKVFQSRCDYCYTAAMTNRWSDSINSDSIFNMRCERGHTILSPRMLHQLRRTILPEGALYTLAVRVVHQSPPEASQPLQIIPCRRERYQILSEADMPRQTGYSGVYRRPTNQICMYTEVELAKKYRLPTNSLYRILDLHDCFFSQKLMDTRGNILVVGDGYGYSSLLTKCLNPDRNVVSWTYIEPSEALPHSLRISKPPMHYKADVQIDSSPSIDRISDIHNSSYPDEFAKVVTKNGITALISDIETVYVSGEKSVASLINLAWNNQIQLGALKLELMTDPLEKVVEYAHNAYQRWELFTLPGANLGGGVLYIGFYGRREKLTGYIIPHSGVETLMDRLATEVDEDRGRLRAEDRDRWEQLDTMESKIHLQQYHKMRLDLWFGSAYLSGYLSEDMTEFFYSVKTSYRPPAISWEKGNQARYLYGSREEILFMSMITVALSSYLEDQDVLREFLSSSGWKLQWKKDKKNPRHWSPYLERSDSQLVWKKNKAMIFKLVSVLRGSKPREEYKMGKASDSIVFRYIPRKVREGEVPLCFPISKVASMSV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH720474
EMBL· GenBank· DDBJ
AZB50487.1
EMBL· GenBank· DDBJ
Viral cRNA
MH720475
EMBL· GenBank· DDBJ
AZB50494.1
EMBL· GenBank· DDBJ
Viral cRNA

Similar Proteins

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