A0A3G5FH51 · A0A3G5FH51_TETHA
- ProteinRelease factor glutamine methyltransferase
- GeneprmC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids280 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Catalytic activity
- L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleic acid binding | |
Molecular Function | protein-(glutamine-N5) methyltransferase activity | |
Molecular Function | protein-glutamine N-methyltransferase activity | |
Biological Process | peptidyl-glutamine methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRelease factor glutamine methyltransferase
- EC number
- Short namesRF MTase
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Enterococcaceae > Tetragenococcus
Accessions
- Primary accessionA0A3G5FH51
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-76 | Release factor glutamine methyltransferase N-terminal | ||||
Sequence: EVLNWASSFLENHGKEGYAIFYVFLARKKWTKTDWLSHMKDKITQKEYDQLQIDLEQLLNDYPPQYLLG | ||||||
Domain | 110-195 | Methyltransferase small | ||||
Sequence: VKQKEEALQVVDVGTGTGAIAATLKLERPAWQISAVDISKNALEVAQVNSDLLEAKVEFYLGNTLEPIKHSIDILIANPPYISQDE |
Sequence similarities
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length280
- Mass (Da)32,261
- Last updated2019-02-13 v1
- Checksum23D1470C93098DA5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP027768 EMBL· GenBank· DDBJ | AYW49448.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BKBM01000066 EMBL· GenBank· DDBJ | GEQ45765.1 EMBL· GenBank· DDBJ | Genomic DNA |