A0A3G5FH51 · A0A3G5FH51_TETHA

Function

function

Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

128020406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site123-127S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site146S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site187S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site187-190substrate

GO annotations

AspectTerm
Molecular Functionnucleic acid binding
Molecular Functionprotein-(glutamine-N5) methyltransferase activity
Molecular Functionprotein-glutamine N-methyltransferase activity
Biological Processpeptidyl-glutamine methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Release factor glutamine methyltransferase
  • EC number
  • Short names
    RF MTase
  • Alternative names
    • N5-glutamine methyltransferase PrmC
    • Protein-(glutamine-N5) MTase PrmC
    • Protein-glutamine N-methyltransferase PrmC

Gene names

    • Name
      prmC
    • ORF names
      C7H83_02565
      , TH8N_21350

Organism names

Accessions

  • Primary accession
    A0A3G5FH51

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-76Release factor glutamine methyltransferase N-terminal
Domain110-195Methyltransferase small

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    280
  • Mass (Da)
    32,261
  • Last updated
    2019-02-13 v1
  • Checksum
    23D1470C93098DA5
MSKQTYQEVLNWASSFLENHGKEGYAIFYVFLARKKWTKTDWLSHMKDKITQKEYDQLQIDLEQLLNDYPPQYLLGYEEFYGRSFKVNSNTLIPRPETEELVEWCLQNTVKQKEEALQVVDVGTGTGAIAATLKLERPAWQISAVDISKNALEVAQVNSDLLEAKVEFYLGNTLEPIKHSIDILIANPPYISQDEWSLMDTSVQRYEPSIALFAENEGLAVYQKIAEQAQEKLTKKGKIFLEIGFNQGGKVEEIFQRSFPQKTIQRKKDLSGNERMLLVH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP027768
EMBL· GenBank· DDBJ
AYW49448.1
EMBL· GenBank· DDBJ
Genomic DNA
BKBM01000066
EMBL· GenBank· DDBJ
GEQ45765.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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