A0A3G3IK46 · A0A3G3IK46_9GAMM
- ProteinDiacylglycerol kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids136 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
Catalytic activity
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
Cofactor
Note: Mn2+, Zn2+, Cd2+ and Co2+ support activity to lesser extents.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 28 | ATP (UniProtKB | ChEBI) | |||
Binding site | 28 | substrate | |||
Binding site | 47 | ATP (UniProtKB | ChEBI) | |||
Binding site | 47 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 49-53 | substrate | |||
Binding site | 74 | substrate | |||
Active site | 88 | Proton acceptor | |||
Binding site | 88 | substrate | |||
Binding site | 95 | ATP (UniProtKB | ChEBI) | |||
Binding site | 95 | a divalent metal cation (UniProtKB | ChEBI) | |||
Binding site | 104-106 | ATP (UniProtKB | ChEBI) | |||
Binding site | 113-114 | ATP (UniProtKB | ChEBI) | |||
Binding site | 117 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent diacylglycerol kinase activity | |
Molecular Function | metal ion binding | |
Biological Process | phosphatidic acid biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDiacylglycerol kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > sulfur-oxidizing symbionts
Accessions
- Primary accessionA0A3G3IK46
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 54-71 | Helical | |||
Transmembrane | 77-94 | Helical | |||
Transmembrane | 115-134 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length136
- Mass (Da)15,276
- Last updated2019-02-13 v1
- ChecksumA54C91103942880F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP024634 EMBL· GenBank· DDBJ | AYQ55944.1 EMBL· GenBank· DDBJ | Genomic DNA |