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A0A3G1RPI1 · A0A3G1RPI1_9RHAB

Function

Catalytic activity

  • GTP + H2O = GDP + phosphate + H+
  • a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
  • a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-homocysteine + H+
    EC:2.1.1.375 (UniProtKB | ENZYME | Rhea)
  • a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine + H+
  • a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H+ = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate
    EC:2.7.7.88 (UniProtKB | ENZYME | Rhea)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componenthost cell cytoplasm
Cellular Componentvirion component
Molecular FunctionATP binding
Molecular Functionhydrolase activity
Molecular FunctionmRNA 5'-cap (guanine-N7-)-methyltransferase activity
Molecular FunctionRNA-dependent RNA polymerase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      L

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MW22
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae

Accessions

  • Primary accession
    A0A3G1RPI1

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain591-777RdRp catalytic
Domain1631-1828Mononegavirus-type SAM-dependent 2'-O-MTase

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,098
  • Mass (Da)
    238,127
  • Last updated
    2019-02-13 v1
  • MD5 Checksum
    658FD2AED3545726AE3BFF9CBD5ABDA3
MDECEYDEFRDQLEDNLLDEEVEFLGTRGKVPARLNNADFNLDSPLLSDECEALISKLQGKYASPLFESNAWKPVLKIKNQLKIQDLSVLDFYPWVGRFASAYVSDTSGAARLLKEANTSASKTWKVPKTFLNLLNNVEIANEDHGSTGVVTHLLQKYIDIMFVLITMNERLTPPTDADNYATCHSEKLEEGSLRVTSKCFGEILLTDRYWIIERRVICNRNYLLMVKDLLSARMHTIISMENRWDNKFSKASIGKFCQLYALGDQILYCMGNDGYRVLKYLEPFCILRLSELARKYRDLIPIMPRFRNYLEDEIRQFGPGTQHLRRLFDSIQDLDDVHLVLQIFGSYRHWGHPTVDYLGGLESLYQQVTQVKKIDDELAQLLASDLAKIVLKSHFRKTKEWAVDSSILPINHPFYHLVENKIWPTPAEEAKFGDKWHTLPLKRCFEIPDFLDPAVIYSDKAHSIQKTELLNHLRRSPNKRIPTKRVLSSFLDNHARNWPEFLKRVDEQGLSDDSLIIGLRAKERELKTQGRFFALMSWELREYFVVTEYLIKEHFVPLFKGLTMADDLTGVMKKLLSSTSGHGHDDYTSLTVSNHLDYSKWNNHQRKESNKYVFEVMGKFLGYPNLISRTHEFFEKSLIYFCNRPDLMAVQGTVVTNKPGFRVCWNGQAGGLEGLRQKGWSILNLLLILRIQKARNTEIKVLAQGDNQVLNMHYKIPQGRDEAETRTFLQEVINNNESIMRDVETWTYRLGLIINKDETVQSCDFLVYGKVPIFRGNLLLPESKRWSRINCVSNDQIPSLGSILGTVGSTALGVSHFSSNYIDPLIKYNFFINLSRVLLEWWNPLLGRSVLEVFPNTDLKQLSYLLKVAFLDPSLGGVCGVNPSRFLIRGFPDPVTESLSFWKYIHAALPLEYQRAISTICHPQVKSFQITDLPRLLENPQTLNLPSATSAQIAIRNEIRGILGKKIHSIKNEVIKSAIVSLKTSEEHLLKFLQSIRPRFPRFLSEFRSSTFLGVCLSLVNLYENSRTIRTQFLKETTKDLSEVIIKSEVRNIKTLTAPPLTTVTALWRCSSEEADRLRFITWGGPVVGATIPHPLELLTAPKNSTDPCCECRLGKNDYVTTIVSSSCLSDISRRGPFTPYLGSKTSESTSIFSPWEKEVTVPLLIRADRMRRCINWFVKADSVLGSSIFNNIKSLTGQDLSTYSVGFMRTGSALHRFSTARQSSGGYSGISPAPLSRMVSTTDTLSDLGITNYDFMFQSLILFCQVSITGLDPKRITPSMHNHIKCHSCVREIKDVVLESEIRYNPPDVTGHTLKWIPGPELAVKLSPMINFLDGNWERVSQSEGSFHVGRVVGYLCGELLFAKKLEAEGGSLLPLGIKNKLSPAEFFSGFVEGCLQASAVDSIHRRFHALQSKPTESLVGTAMFVINKLTKNTVFLSFIGSGSLFNYVISSTHRVPPSYPSSPLHIGQIVYSFLLRLLIQRTKRAALPPVSRKLWLFSDILSPNLSGPFILSRRITQLLLKPRITKQDLDEIRELKAIEISCRGSTDGITLRFPGKYIGGVTTSRSEVRHAVAAYPSLAETPSVTVNFGEEINGHVESESVEFILCPPEDIKCKRVPRILNPLISGLRTFQMATGSHYKLRCILNHYQTTYRDFLCGGDGSGGLTAYLLRRNPSSRGLFNSLLNLGGINLRGAKPGPPSAVTALGESSTRCLNIATCWRDPSDLNDKHTWETLFQYKMKYRMLIDLIVLDFEENKPGNTIIEENILTTGLKILEPRGSIIYKTYCHRIADNSLTDFLTRCGRLFKNINLCQTDFTSSHSSEIYIYLDNYMADSIGQRYPNIPKLKQFIENRFCFRTAEEELNRAQKVRKLNRLRGVPMSLVPDLLSELIQWLDMAGTYAGQSNSLAHLILHTKYLPRTLTRVILSVVGNCVFRFVFPAKRSSPPSDPKLENFMSLWASLHLWESLVNDDATKHQQTLNIINSDCPVSFYLREEGEHLYPCVEVGRKINLVKRVRLLGKGAAMGQGIRLLDRLSNYPKTTIPTGRELSQFHGRLSSATLDKHSNLSLVPGKIDRMPDPTKHRILVERAEPEGGWRE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH453880
EMBL· GenBank· DDBJ
AXF38754.1
EMBL· GenBank· DDBJ
Viral cRNA

Similar Proteins

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