A0A3D9DE00 · A0A3D9DE00_9FLAO

Function

function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site72FMN (UniProtKB | ChEBI)
Active site102Proton donor
Binding site141FMN (UniProtKB | ChEBI)
Binding site171FMN (UniProtKB | ChEBI)
Binding site228-229FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionRNA binding
Molecular FunctiontRNA dihydrouridine synthase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-dihydrouridine synthase
  • EC number

Gene names

    • ORF names
      DRF60_14345

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KCTC 22547
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Weeksellaceae > Chryseobacterium group > Chryseobacterium

Accessions

  • Primary accession
    A0A3D9DE00

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-318DUS-like FMN-binding

Sequence similarities

Belongs to the dus family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    331
  • Mass (Da)
    37,851
  • Last updated
    2019-01-16 v1
  • Checksum
    A72EAA2191FE6977
MVKIGNIELPEFPLLLAPMEDVSDPPFRRLCKMHGADLMYSEFISSEGLIRDAMKSRKKLDIFDYERPVGIQIFGGDEEAMAMSARIVETVNPDLVDINFGCPVKKVVCKGAGAGVLKDIDLMVRLTKAVVNSTHLPVTVKTRLGWDSTSINIDEVAERLQETGIKALTIHARTRAQMYKGEADWEHISRIKQNPNIEIPIFGNGDIDSPEKALEYKQKYACDGIMIGRAAIGYPWIFNEIKHFFKTGEHLPEPVIADRLLAVRQHAEWSAEWKGEKLGLIEMRQHYSNYFRGVPHFKEFRKKFLEVFTLEEMNALIKETQQFYEEYQAQV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QNUH01000012
EMBL· GenBank· DDBJ
REC76061.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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