A0A3C1WZI1 · A0A3C1WZI1_9GAMM
- ProteinType III pantothenate kinase
- GenecoaX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids226 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
Catalytic activity
- (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H+
Cofactor
Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )
Note: A monovalent cation. Ammonium or potassium.
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 9-16 | ATP (UniProtKB | ChEBI) | |||
Binding site | 75 | substrate | |||
Binding site | 82-85 | substrate | |||
Active site | 84 | Proton acceptor | |||
Binding site | 105 | K+ (UniProtKB | ChEBI) | |||
Binding site | 108 | ATP (UniProtKB | ChEBI) | |||
Binding site | 156 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pantothenate kinase activity | |
Biological Process | coenzyme A biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameType III pantothenate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria
Accessions
- Primary accessionA0A3C1WZI1
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length226
- Mass (Da)24,781
- Last updated2019-01-16 v1
- ChecksumDC360EB8CEAFE66A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DMQZ01000038 EMBL· GenBank· DDBJ | HAO44584.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DMRF01000062 EMBL· GenBank· DDBJ | HAP05553.1 EMBL· GenBank· DDBJ | Genomic DNA |