A0A3C1WZI1 · A0A3C1WZI1_9GAMM

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site9-16ATP (UniProtKB | ChEBI)
Binding site75substrate
Binding site82-85substrate
Active site84Proton acceptor
Binding site105K+ (UniProtKB | ChEBI)
Binding site108ATP (UniProtKB | ChEBI)
Binding site156substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      DCQ55_01835
      , DCQ71_02355

Organism names

Accessions

  • Primary accession
    A0A3C1WZI1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    226
  • Mass (Da)
    24,781
  • Last updated
    2019-01-16 v1
  • Checksum
    DC360EB8CEAFE66A
MDKITLFIDVGNTAVKWLFDGDYQSVAVTEFSPTLLPKAKRIFVSCVGDKMLLEGLKNTIFVESQATFNIFKSAYKNADELGVDRFLAMIATINQYPDQTRLIVDAGSALTFDLVLADGTHQGGLIMPGLGKLRRSFDQFCTESQQLHNHKLADNTSDAWACGTGQMFTSVINAQIEHYLDEFGDLVVVLSGGDSKLLALRLSHAVKLQPNLVLEGLSIYAQTLTA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DMQZ01000038
EMBL· GenBank· DDBJ
HAO44584.1
EMBL· GenBank· DDBJ
Genomic DNA
DMRF01000062
EMBL· GenBank· DDBJ
HAP05553.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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