A0A3C1GFJ4 · A0A3C1GFJ4_9BACT

Function

function

Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site309substrate

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenosylcobinamide-GDP ribazoletransferase activity
Molecular Functioncobalamin 5'-phosphate synthase activity
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide-GDP ribazoletransferase
  • EC number
  • Alternative names
    • Cobalamin synthase
    • Cobalamin-5'-phosphate synthase

Gene names

    • Name
      cobS
    • ORF names
      DCQ64_18785

Organism names

Accessions

  • Primary accession
    A0A3C1GFJ4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-48Helical
Transmembrane105-124Helical
Transmembrane177-209Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the CobS family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    456
  • Mass (Da)
    47,643
  • Last updated
    2019-01-16 v1
  • Checksum
    057D3F02C7EBD3E7
MASLILAIRFLTIVPVPGREAAGPGALGRAAWWFPAVGLGLGAGLVLVDRLLTRAFPPLLAALLVVSLWKVATGGIHLDGLADCLDGLGGRDPGHRVAIMRDSRIGVFGALGLILSFLIGITALGELPGDVRWRALLLAPVVGRLSPLVAGACFRAATPEAGSGSAFMASLSRWAPALSVVWAGVVAALLLELPGLLALAVALAGVLLWSGFLSRRLGGLTGDALGAGVELAELGVLLALAAAAHVMQDLTPTVIYLVRHGAVVGAESRRFIGHLDVPLSPLGEAQCEALARRLATVALAAVYSSDLLRSRRSAEILAAPHGLRTEALPGLREFAMGRWEGLTAEEIRARDPVAFEEWMADIGRFQFPEGEHLEQVAVRAWRAFEGIVAAHAGARVAVVSHGGTNRAILCRALGIPLGRILALGQDYAALSVLEAAPEGWRLRLLNHCEPLLAPSP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DMMU01000541
EMBL· GenBank· DDBJ
HAM57340.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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