A0A3B9P0Y3 · A0A3B9P0Y3_9PROT
- ProteinMultifunctional fusion protein
- Genecmk
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids647 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Catalytic activity
- 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphateThis reaction proceeds in the forward direction.
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 25 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 25 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 26 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 30 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 97 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 125 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 171 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 172 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 173 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 173 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 199 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Active site | 316 | Proton acceptor | |||
Binding site | 316 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 343 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 347 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 389 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 414 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 437-445 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 3-phosphoshikimate 1-carboxyvinyltransferase activity | |
Molecular Function | ATP binding | |
Molecular Function | CMP kinase activity | |
Molecular Function | dCMP kinase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | pyrimidine nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended name3-phosphoshikimate 1-carboxyvinyltransferase
- EC number
- Alternative names
- Recommended nameCytidylate kinase
- EC number
- Short namesCK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Nitrosomonadales > Gallionellaceae
Accessions
- Primary accessionA0A3B9P0Y3
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 16-421 | Enolpyruvate transferase | |||
Domain | 433-641 | Cytidylate kinase | |||
Sequence similarities
Belongs to the EPSP synthase family.
Belongs to the cytidylate kinase family. Type 1 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length647
- Mass (Da)69,134
- Last updated2019-01-16 v1
- Checksum093FC8FE82EA0EE8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DMCN01000098 EMBL· GenBank· DDBJ | HAF45450.1 EMBL· GenBank· DDBJ | Genomic DNA |