A0A3B6VCA5 · A0A3B6VCA5_BRAHW
- ProteinUDP-3-O-acyl-N-acetylglucosamine deacetylase
- GenelpxC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids434 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
Catalytic activity
- a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate
Cofactor
Pathway
Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity | |
Molecular Function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity | |
Biological Process | lipid A biosynthetic process | |
Biological Process | phosphorelay signal transduction system |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-3-O-acyl-N-acetylglucosamine deacetylase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Spirochaetota > Spirochaetia > Brachyspirales > Brachyspiraceae > Brachyspira
Accessions
- Primary accessionA0A3B6VCA5
Proteomes
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 63 | 4-aspartylphosphate | ||||
Sequence: D |
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 14-128 | Response regulatory | ||||
Sequence: NILIIDDEEDILTTCQNILEDEGYGVDIAKNYKEAEDILNSKNVNLVFLDVWLPDVDGLDILANIKEKHPNTVVIMMSGHAGVETAVRATKMGAYDFLEKPISISKLLSSCEDVF |
Family and domain databases
Sequence
- Sequence statusComplete
- Length434
- Mass (Da)48,341
- Last updated2018-12-05 v1
- ChecksumE2D48ECDED8E5639
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001357 EMBL· GenBank· DDBJ | ACN83743.1 EMBL· GenBank· DDBJ | Genomic DNA |