A0A3B4ZZG8 · A0A3B4ZZG8_9TELE
- ProteinLarge neutral amino acids transporter small subunit 2
- GeneLOC103358414
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids526 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 3,3',5-triiodo-L-thyronine(out) = 3,3',5-triiodo-L-thyronine(in)This reaction proceeds in the forward direction.
- 3,3'-diiodo-L-thyronine(out) = 3,3'-diiodo-L-thyronine(in)This reaction proceeds in the forward direction.
- L-alanine(in) + L-phenylalanine(out) = L-alanine(out) + L-phenylalanine(in)
- L-cysteine(in) + L-phenylalanine(out) = L-cysteine(out) + L-phenylalanine(in)
- L-cysteine(out) + L-methionine(in) = L-cysteine(in) + L-methionine(out)
- L-dopa(out) + L-phenylalanine(in) = L-dopa(in) + L-phenylalanine(out)
- L-glutamine(in) + L-phenylalanine(out) = L-glutamine(out) + L-phenylalanine(in)
- L-histidine(in) + L-phenylalanine(out) = L-histidine(out) + L-phenylalanine(in)
- L-isoleucine(in) + L-phenylalanine(out) = L-isoleucine(out) + L-phenylalanine(in)
- L-leucine(in) + L-phenylalanine(out) = L-leucine(out) + L-phenylalanine(in)
- L-leucine(out) + L-methionine(in) = L-leucine(in) + L-methionine(out)
- L-leucine(out) + S-methylmercury-L-cysteine(in) = L-leucine(in) + S-methylmercury-L-cysteine(out)
- L-methionine(in) + L-phenylalanine(out) = L-methionine(out) + L-phenylalanine(in)
- L-methionine(in) + S-methylmercury-L-cysteine(out) = L-methionine(out) + S-methylmercury-L-cysteine(in)
- L-phenylalanine(out) + L-serine(in) = L-phenylalanine(in) + L-serine(out)
- L-phenylalanine(out) + L-tryptophan(in) = L-phenylalanine(in) + L-tryptophan(out)
- L-phenylalanine(out) + L-valine(in) = L-phenylalanine(in) + L-valine(out)
- L-phenylalanine(out) + S-methylmercury-L-cysteine(in) = L-phenylalanine(in) + S-methylmercury-L-cysteine(out)
- glycine(in) + L-phenylalanine(out) = glycine(out) + L-phenylalanine(in)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | basolateral plasma membrane | |
Cellular Component | lateral plasma membrane | |
Molecular Function | antiporter activity | |
Molecular Function | L-amino acid transmembrane transporter activity | |
Molecular Function | neutral L-amino acid transmembrane transporter activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameLarge neutral amino acids transporter small subunit 2
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Pomacentridae > Stegastes
Accessions
- Primary accessionA0A3B4ZZG8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Basolateral cell membrane ; Multi-pass membrane protein
Lateral cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 35-55 | Helical | ||||
Sequence: IGLVSACGIIVGNIIGSGIFV | ||||||
Transmembrane | 67-93 | Helical | ||||
Sequence: VGVALIVWIITGIITAIGALCYAELGV | ||||||
Transmembrane | 114-138 | Helical | ||||
Sequence: GFLRLWIAVLVIYPTNQAVIALTFS | ||||||
Transmembrane | 158-178 | Helical | ||||
Sequence: LLAAVCLLLLTWVNCSSVRWA | ||||||
Transmembrane | 190-212 | Helical | ||||
Sequence: LLALALIIIMGIVQICKGEYYWL | ||||||
Transmembrane | 224-243 | Helical | ||||
Sequence: YDVGLIALAFLQGSFAYGGW | ||||||
Transmembrane | 264-285 | Helical | ||||
Sequence: IFISIPLVTFVYVFANIAYVTA | ||||||
Transmembrane | 305-325 | Helical | ||||
Sequence: LLGVMSWIMPISVALSTFGGV | ||||||
Transmembrane | 360-382 | Helical | ||||
Sequence: IPALLFTCLSTLLMLCTSDMYTL | ||||||
Transmembrane | 388-406 | Helical | ||||
Sequence: FINYLFYGVTVAGQIVLRF | ||||||
Transmembrane | 418-439 | Helical | ||||
Sequence: SLIWPVIYLIFWAFLLIFSLYS | ||||||
Transmembrane | 445-464 | Helical | ||||
Sequence: GIGLAIMLTGVPVYFLGVYW |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-17 | Polar residues | ||||
Sequence: MTDGARQRSSTSASAKD | ||||||
Region | 1-20 | Disordered | ||||
Sequence: MTDGARQRSSTSASAKDAAA | ||||||
Region | 493-526 | Disordered | ||||
Sequence: ESSSSGSGEEGEEMKEAMSPLSKEDGDNHKSADC | ||||||
Compositional bias | 500-526 | Basic and acidic residues | ||||
Sequence: GEEGEEMKEAMSPLSKEDGDNHKSADC |
Sequence similarities
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length526
- Mass (Da)57,046
- Last updated2018-12-05 v1
- Checksum6B6791C56A978369
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-17 | Polar residues | ||||
Sequence: MTDGARQRSSTSASAKD | ||||||
Compositional bias | 500-526 | Basic and acidic residues | ||||
Sequence: GEEGEEMKEAMSPLSKEDGDNHKSADC |
Keywords
- Technical term