A0A3B4FC60 · A0A3B4FC60_9CICH
- ProteinPhospholipid phosphatase 1
- GenePLPP1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids282 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O = (9Z-octadecenoyl)-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- H2O + N-(9Z-octadecenoyl)-ethanolamine phosphate = N-(9Z-octadecenoyl) ethanolamine + phosphateThis reaction proceeds in the forward direction.
- H2O + N-(octanoyl)-sphing-4-enine-1-phosphate = N-octanoylsphing-4-enine + phosphateThis reaction proceeds in the forward direction.
- H2O + monoacyl-sn-glycero-3-phosphate = a monoacylglycerol + phosphateThis reaction proceeds in the forward direction.
- H2O + sphing-4-enine 1-phosphate = phosphate + sphing-4-enineThis reaction proceeds in the forward direction.
- an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphateThis reaction proceeds in the forward direction.
Pathway
Lipid metabolism; phospholipid metabolism.
Phospholipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | caveola | |
Molecular Function | lysophosphatidic acid phosphatase activity | |
Molecular Function | phosphatidate phosphatase activity | |
Biological Process | phospholipid dephosphorylation | |
Biological Process | phospholipid metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhospholipid phosphatase 1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Cichlomorphae > Cichliformes > Cichlidae > African cichlids > Pseudocrenilabrinae > Haplochromini > Pundamilia
Accessions
- Primary accessionA0A3B4FC60
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Membrane raft ; Multi-pass membrane protein
Membrane, caveola ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 7-27 | Helical | ||||
Sequence: IPFVLLDIVCLVLGGLPLAAY | ||||||
Transmembrane | 59-79 | Helical | ||||
Sequence: VLYTVGFALPISCMIVGECLL | ||||||
Transmembrane | 91-111 | Helical | ||||
Sequence: FGSYVACLYKAIGTFVFGAAM | ||||||
Transmembrane | 166-186 | Helical | ||||
Sequence: LSFYSGHSSFSMYCMLFLALY | ||||||
Transmembrane | 198-217 | Helical | ||||
Sequence: LLRPTIQFFLIAASVYTGLS | ||||||
Transmembrane | 229-251 | Helical | ||||
Sequence: VLTGLIQGALMALLVVFFVSDFF |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 102-244 | Phosphatidic acid phosphatase type 2/haloperoxidase | ||||
Sequence: IGTFVFGAAMSQSLTDIAKYSIGRLRPHFLDLCRPDWKLINCSAGTYIEDFTCTGDAKQVNEARLSFYSGHSSFSMYCMLFLALYLQARLQADCARLLRPTIQFFLIAASVYTGLSRVSDYKHHWSDVLTGLIQGALMALLVV | ||||||
Region | 261-282 | Disordered | ||||
Sequence: ADIPHTTLQETPTNGNHFESPN | ||||||
Compositional bias | 266-282 | Polar residues | ||||
Sequence: TTLQETPTNGNHFESPN |
Sequence similarities
Belongs to the PA-phosphatase related phosphoesterase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length282
- Mass (Da)31,555
- Last updated2018-12-05 v1
- Checksum61284CC70C52F0AA
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 266-282 | Polar residues | ||||
Sequence: TTLQETPTNGNHFESPN |
Keywords
- Technical term