A0A3B4EIU2 · A0A3B4EIU2_PYGNA

Function

function

Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

Catalytic activity

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site16-23GTP (UniProtKB | ChEBI)
Binding site81-85GTP (UniProtKB | ChEBI)
Binding site135-138GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrial matrix
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmitochondrial ribosome binding
Biological Processpositive regulation of translation
Biological Processtranslation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Tr-type G domain-containing protein

Gene names

    • Name
      GUF1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Characiformes > Characoidei > Pygocentrus

Accessions

  • Primary accession
    A0A3B4EIU2

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-188Tr-type G

Sequence similarities

Belongs to the GTP-binding elongation factor family. LepA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    559
  • Mass (Da)
    62,840
  • Last updated
    2018-12-05 v1
  • Checksum
    8955CB58ABD3EA68
MSEFPVDRIRNFSIIAHIDHGKSTLADRLLELTGAIAKTECNKQVLDKLQVERERGITVKAQTASLFYQHEGQTYLLNLIDTPGHVDFSYEVSRSISACQGVLLIVDANQGIQAQTVANFYLAFEAQLTIIPIINKIDLKNADPERVEKQIEKIFDIPKEECIRISAKLGTNVDQVLQEVVKRIPSPTAKVEEPFKALVFDSTFDHYRGVVANIAVFGGQVSKGDRIVSAHMGKTYEVNELGILRPDEHPTEKLYAGQVGYVIAGMKEVKEAQIGDTLYLHKQPVETLPGFKPAKSMVFAGIYPMDQSEYTTLRSAVEKLTLNDSSVTVQRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVIVTAPTVPYKAVMSSPKLIKSRRAIQKNMVYIDDHRVMMKYLFPLNEIVVDFYDQLKSMSSGYASFDYEDAGYEPAELIKIDFLLNGKPVEELTTIVHKDRAYSMGKAMCERLRDSIPRQMFEIAVQAAIGSKVIARETIKAYRKNVLAKCYGGDITRKMKLLKKQAEGKKKMRRIGNVEVPKDAFINVLKKK

Genome annotation databases

Similar Proteins

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