A0A3B4EIU2 · A0A3B4EIU2_PYGNA
- ProteinTr-type G domain-containing protein
- GeneGUF1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids559 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 16-23 | GTP (UniProtKB | ChEBI) | |||
Binding site | 81-85 | GTP (UniProtKB | ChEBI) | |||
Binding site | 135-138 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial matrix | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | mitochondrial ribosome binding | |
Biological Process | positive regulation of translation | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameTr-type G domain-containing protein
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Characiformes > Characoidei > Pygocentrus
Accessions
- Primary accessionA0A3B4EIU2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-188 | Tr-type G | |||
Sequence similarities
Belongs to the GTP-binding elongation factor family. LepA subfamily.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length559
- Mass (Da)62,840
- Last updated2018-12-05 v1
- Checksum8955CB58ABD3EA68