A0A3B3TD72 · A0A3B3TD72_9TELE

  • Protein
    RAF proto-oncogene serine/threonine-protein kinase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site363ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionprotein serine/threonine kinase activity
Biological ProcessRas protein signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RAF proto-oncogene serine/threonine-protein kinase
  • EC number
  • Alternative names
    • Raf-1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Osteoglossocephala > Osteoglossomorpha > Osteoglossiformes > Mormyridae > Paramormyrops

Accessions

  • Primary accession
    A0A3B3TD72

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain55-130RBD
Domain137-183Phorbol-ester/DAG-type
Region280-320Disordered
Compositional bias282-300Polar residues
Compositional bias301-320Basic and acidic residues
Domain337-600Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    600
  • Mass (Da)
    67,085
  • Last updated
    2018-12-05 v1
  • Checksum
    B6B7FA9BCCE487C1
MEHIQGALKTLSNGFGLKDSIFEGPCMSPTIDQGFTYCRRSSDEGKSPDSTKTSSTIRVYLPNKQRTVVNVRPGMTLHSCLIKALVVRGLQPQCCAVFKLHPGQRSKKSRMDWNTDSTTLIGEELLVEVLDHVPLTTHNFVRKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLSFSIPGESGGPSVPPHTSRRMRESLSRFPVGSQHRHSTPHAFNYNVCYPPPGGALSQRQRSTSTPNVHISTNIAVDSTVIEDAIRGYESGSPQSHSPTGWSQSKTPAPTHREKSHSSSMQEKHRIRPRDKRDSSYYWEIEASEVVLLSRIGSGSFGTVYKGKWHGDVAVKILKVTDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMAKDSLAIVAQWCEGSSLFKHLHVQETNFKMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGIVLFELMAGDLPYSHIANRDQVILGTISGTCVGPTITTIIIACFPPQHSHCKYLQSCSLISSPLSTGLYFGFCFGGL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias282-300Polar residues
Compositional bias301-320Basic and acidic residues

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp