A0A3B3HX68 · A0A3B3HX68_ORYLA
- ProteinTriokinase/FMN cyclase
- Genetkfc
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids580 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.
Catalytic activity
- D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 57-60 | substrate | |||
Binding site | 110 | substrate | |||
Binding site | 115 | substrate | |||
Active site | 222 | Tele-hemiaminal-histidine intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | FAD-AMP lyase (cyclizing) activity | |
Molecular Function | glycerone kinase activity | |
Biological Process | glycerol catabolic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriokinase/FMN cyclase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Beloniformes > Adrianichthyidae > Oryziinae > Oryzias
Accessions
- Primary accessionA0A3B3HX68
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Interaction
Subunit
Homodimer. Interacts with IFIH1 (via the CARD domains), the interaction is inhibited by viral infection.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length580
- Mass (Da)59,928
- Last updated2018-12-05 v1
- MD5 ChecksumAB26B9858395510163A0BDB70AADB388
Keywords
- Technical term