Somatic cell hybrid mapping on mouse chromosome 11 (MMU11): assignment of markers relative to two breakpoints in band D.Morris D.J., Adler I.D., Robinson T.J.View abstractCategoriesPhenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCGenomics 15:323-331 (1993)Mapped to99+
Long Noncoding RNA U90926 Is Induced in Activated Macrophages, Is Protective in Endotoxic Shock, and Encodes a Novel Secreted Protein.Sabikunnahar B., Caldwell S., Varnum S., Hogan T., Cooper A., Lahue K.G., Bivona J.J., Cousens P.M., Symeonides M.[...], Krementsov D.N.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCJ. Immunol. 0:0-0 (2023)Cited in1Mapped to7
MKK6 deficiency promotes cardiac dysfunction through MKK3-p38gamma/delta- mTOR hyperactivation.Romero-Becerra R., Mora A., Manieri E., Nikolic I., Santamans A.M., Montalvo-Romeral V., Cruz F.M., Rodriguez E., Leon M.[...], Sabio G.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCElife 11:e75250-e75250 (2022)Mapped to31
p38alpha-MAPK-deficient myeloid cells ameliorate symptoms and pathology of APP-transgenic Alzheimer's disease mice.Luo Q., Schnoder L., Hao W., Litzenburger K., Decker Y., Tomic I., Menger M.D., Liu Y., Fassbender K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCAging Cell 21:e13679-e13679 (2022)Mapped to17
FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.Zhang Y., Hao J., Tarrago M.G., Warner G.M., Giorgadze N., Wei Q., Huang Y., He K., Chen C.[...], Hu J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCCell Rep 36:109481-109481 (2021)Mapped to99+
Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway.Alicea-Torres K., Sanseviero E., Gui J., Chen J., Veglia F., Yu Q., Donthireddy L., Kossenkov A., Lin C.[...], Gabrilovich D.I.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCNat Commun 12:1717-1717 (2021)Mapped to48
Expression of a constitutively active p38alpha mutant in mice causes early death, anemia, and accumulation of immunosuppressive cells.Darlyuk-Saadon I., Heng C.K.M., Bai C., Gilad N., Yu W.P., Meng Huang Mok M., Wong W.S.F., Engelberg D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCFEBS J 288:3978-3999 (2021)Mapped to5
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.Schriever S.C., Kabra D.G., Pfuhlmann K., Baumann P., Baumgart E.V., Nagler J., Seebacher F., Harrison L., Irmler M.[...], Pfluger P.T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCJ Clin Invest 130:6093-6108 (2020)Mapped to22
Neuronal deficiency of p38alpha-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.Schnoder L., Gasparoni G., Nordstrom K., Schottek A., Tomic I., Christmann A., Schafer K.H., Menger M.D., Walter J.[...], Liu Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCFASEB J 34:9628-9649 (2020)Mapped to8
Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway.He D., Wu H., Xiang J., Ruan X., Peng P., Ruan Y., Chen Y.G., Wang Y., Yu Q.[...], Li B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCNat Commun 11:37-37 (2020)Mapped to99+
The noncanonical BMP signaling pathway plays an important role in club cell regeneration.Shafiquzzaman M., Biswas S., Li P., Mishina Y., Li B., Liu H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCStem Cells 38:437-450 (2020)Mapped to17
P38alpha MAPK coordinates the activities of several metabolic pathways that together induce atrophy of denervated muscles.Odeh M., Tamir-Livne Y., Haas T., Bengal E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCFEBS J 287:73-93 (2020)Mapped to5
Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling.Kase Y., Otsu K., Shimazaki T., Okano H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCStem Cell Reports 12:1313-1328 (2019)Mapped to5
Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.Celaya A.M., Sanchez-Perez I., Bermudez-Munoz J.M., Rodriguez-de la Rosa L., Pintado-Berninches L., Perona R., Murillo-Cuesta S., Varela-Nieto I.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCElife 8:e39159-e39159 (2019)Mapped to99+
New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to beta-adrenergic stimulation-induced cardiac fibrosis.Takahara S., Inoue S.I., Miyagawa-Tomita S., Matsuura K., Nakashima Y., Niihori T., Matsubara Y., Saiki Y., Aoki Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCEBioMedicine 42:43-53 (2019)Mapped to81
Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2<sup>-/-</sup> Mice.Chung C., Ha S., Kang H., Lee J., Um S.M., Yan H., Yoo Y.E., Yoo T., Jung H.[...], Kim E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCBiol Psychiatry 85:534-543 (2019)Mapped to94
Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.Chen Y., Wang Z., Chen Y., Zhang Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCCell Tissue Res 376:199-210 (2019)Mapped to52
Neuronal MAP kinase p38alpha inhibits c-Jun N-terminal kinase to modulate anxiety-related behaviour.Stefanoska K., Bertz J., Volkerling A.M., van der Hoven J., Ittner L.M., Ittner A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCSci Rep 8:14296-14296 (2018)Mapped to13
Targeted ablation of p38alpha MAPK suppresses denervation-induced muscle atrophy.Yuasa K., Okubo K., Yoda M., Otsu K., Ishii Y., Nakamura M., Itoh Y., Horiuchi K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCSci Rep 8:9037-9037 (2018)Mapped to5
Metabolic benefits of inhibition of p38alpha in white adipose tissue in obesity.Zhang S., Cao H., Li Y., Jing Y., Liu S., Ye C., Wang H., Yu S., Peng C.[...], Ying H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCPLoS Biol 16:e2004225-e2004225 (2018)Mapped to7
Expression of ILK in renal stroma is essential for multiple aspects of renal development.Gong X., Guo X., Huang R., Liao H., Zhang Q., Yan J., Luo L., Zhang Q., Qiu A.[...], Liang X.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCAm J Physiol Renal Physiol 315:F374-F385 (2018)Mapped to67
Age-dependent regulation of antioxidant genes by p38alpha MAPK in the liver.Perez S., Rius-Perez S., Tormos A.M., Finamor I., Nebreda A.R., Talens-Visconti R., Sastre J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCRedox Biol 16:276-284 (2018)Mapped to5
Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death.Liu X., Hayano S., Pan H., Inagaki M., Ninomiya-Tsuji J., Sun H., Mishina Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCGenesis 56:e23093-e23093 (2018)Mapped to55
Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool.Zega K., Jovanovic V.M., Vitic Z., Niedzielska M., Knaapi L., Jukic M.M., Partanen J., Friedel R.H., Lang R., Brodski C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCFront Mol Neurosci 10:372-372 (2017)Mapped to99+
Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.Inoue S.I., Takahara S., Yoshikawa T., Niihori T., Yanai K., Matsubara Y., Aoki Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1346865PubMedEurope PMCHum Mol Genet 26:4715-4727 (2017)Mapped to99+