A0A3B1KEY6 · A0A3B1KEY6_ASTMX
- ProteinProtein-glutamine gamma-glutamyltransferase 2
- GeneTGM2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids582 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- L-glutaminyl-[protein] + (R)-noradrenaline = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
- L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
- L-glutaminyl-[protein] + dopamine = 5-dopaminyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
- L-glutaminyl-[protein] + histamine = 5-histaminyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome | |
Cellular Component | collagen-containing extracellular matrix | |
Cellular Component | cytosol | |
Cellular Component | extracellular region | |
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | GTP binding | |
Molecular Function | peptidase activity | |
Molecular Function | protein-glutamine gamma-glutamyltransferase activity | |
Biological Process | nervous system development | |
Biological Process | peptide cross-linking | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein-glutamine gamma-glutamyltransferase 2
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Characiformes > Characoidei > Characidae > Astyanax
Accessions
- Primary accessionA0A3B1KEY6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 262-338 | Transglutaminase-like | ||||
Sequence: CKSVRYGQCWVFAGVGCTVARALGIPCRLITNFESAHDTNGDLKIETYVGEDGRMVKESHCWSSVMCCGPVPVKAIK |
Sequence similarities
Belongs to the transglutaminase superfamily. Transglutaminase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length582
- Mass (Da)64,381
- Last updated2018-12-05 v1
- Checksum1C179052CFB16791
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A3B1K119 | A0A3B1K119_ASTMX | TGM2 | 589 | ||
W5K0I5 | W5K0I5_ASTMX | TGM2 | 586 | ||
A0A3B1KJ77 | A0A3B1KJ77_ASTMX | TGM2 | 560 |
Keywords
- Technical term