A0A3B0MQW6 · A0A3B0MQW6_9RHOB

  • Protein
    tRNA modification GTPase MnmE
  • Gene
    mnmE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

138250100150200250300350
TypeIDPosition(s)Description
Binding site9(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site31(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site71(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)
Binding site176K+ (UniProtKB | ChEBI)
Binding site176-181GTP (UniProtKB | ChEBI)
Binding site180Mg2+ (UniProtKB | ChEBI)
Binding site195K+ (UniProtKB | ChEBI)
Binding site195-201GTP (UniProtKB | ChEBI)
Binding site197K+ (UniProtKB | ChEBI)
Binding site200K+ (UniProtKB | ChEBI)
Binding site201Mg2+ (UniProtKB | ChEBI)
Binding site220-223GTP (UniProtKB | ChEBI)
Binding site382(6S)-5-formyl-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmetal ion binding
Biological ProcesstRNA methylation
Biological ProcesstRNA wobble uridine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA modification GTPase MnmE
  • EC number

Gene names

    • Name
      mnmE
    • Synonyms
      trmE
    • ORF names
      ROE7235_01042

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CECT 7235
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Roseibaca

Accessions

  • Primary accession
    A0A3B0MQW6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain166-305TrmE-type G

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    382
  • Mass (Da)
    40,289
  • Last updated
    2018-12-05 v1
  • Checksum
    6800F98409362FBB
MLRDGSGERLDSALVVAFAKGASFTGEDVAELMVHGSLATVTAIERCLAQDHGLRMAQPGEFTRRALDNGMMDLTQVEALSDLLEAETESQRRQALRVLDGAIGKVVAGWRAHLVKAAALVETSIDFVEEDVGNFDAEILAELRAVADGLTAEIAGQRARERVQTGFEVALVGPVNAGKSSLLNALAGREAAITSDIAGTTRDVLEVRMDVGGYAVTFLDTAGLRDTAEQVEAIGIARGRARAEQADLRIILQPADYIGTVSPSDPQDIVVRSKSDLGPASDDGISVVTGAGLDWLMAEVTNRLSQMTARDGVTVRARHQTAMKDGLAAISNAIDKIGSGSYIEELVAADIRIAITALDSLIGVVDVEDVLGDIFSSFCIGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UIHC01000007
EMBL· GenBank· DDBJ
SUZ31304.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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