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A0A3A6VPK7 · A0A3A6VPK7_LEGPN

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site46substrate
Binding site46-47ATP (UniProtKB | ChEBI)
Binding site54ATP (UniProtKB | ChEBI)
Site54Transition state stabilizer
Binding site78substrate
Binding site110substrate
Binding site124substrate
Binding site125-127ATP (UniProtKB | ChEBI)
Binding site135ATP (UniProtKB | ChEBI)
Binding site160-166ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • ORF names
      D1H98_01370

Organism names

Accessions

  • Primary accession
    A0A3A6VPK7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Sequence similarities

Belongs to the bacterial CoaD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    197
  • Mass (Da)
    22,368
  • Last updated
    2018-12-05 v1
  • MD5 Checksum
    1CA5205A65DBB39A6CFABFF0AC06C4DF
MSNVLSHSLLTSIPFFYSFSIYNTLDCFYMQMVINEMKQKAIYPGTFDPVTNGHIDIITRASTIFPELIVAVASNKNKRPYLSWETRISLLEESVGHLTGVRVVGFDNLLIDFVLEQSAGIILRGLRAVSDFEYEFQLAGMNRKLSKKVETLFLTPAEHLMYISSTLVREIAALNGDISQFVPPNVVRELKKRQNEI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QWDR01000001
EMBL· GenBank· DDBJ
RJY33486.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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