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A0A3A6UDT3 · A0A3A6UDT3_LEGPN

Function

function

Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site125S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site144S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site152S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionRNA binding
Molecular FunctiontRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (cytidine(34)-2'-O)-methyltransferase activity
Biological Processwobble position cytosine ribose methylation
Biological Processwobble position uridine ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL

Gene names

    • Name
      trmL
    • ORF names
      D1H98_07185

Organism names

Accessions

  • Primary accession
    A0A3A6UDT3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain27-164tRNA/rRNA methyltransferase SpoU type

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    174
  • Mass (Da)
    20,070
  • Last updated
    2018-12-05 v1
  • MD5 Checksum
    313942BCF661E5033296BA1D37E7D76E
MHPATLFLALNKSIKMAARMLLENHMIHIALYQPEIPPNTGNIIRLCANTGAQLHLIHPLGFTLEDKQMRRAGLDYHQWASILHYENWQTFLQSHSQRRLFCCSAKGKVKYSDVDYKADDILLFGPESCGLPQQILNQYSTIRIPMRENNRSLNLSNAVAIILYEAWRQMGFNM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QWDR01000001
EMBL· GenBank· DDBJ
RJY34562.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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