A0A3A5S8L0 · A0A3A5S8L0_9BACE

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

Type
IDPosition(s)Description
Site18Important for substrate specificity
Active site77Proton acceptor
Site78Important for substrate specificity
Site160Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function8-oxo-(d)RTP hydrolase activity
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • Name
      maf
    • ORF names
      DXA24_06000

Organism names

  • Taxonomic identifier
  • Strain
    • CF01-10NS
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides

Accessions

  • Primary accession
    A0A3A5S8L0

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    193
  • Mass (Da)
    21,648
  • Last updated
    2018-12-05 v1
  • MD5 Checksum
    427F927E918DF967342E176B0329144D
MLDNLNKYQIILASNSPRRKELMSGLGVDYVVRTLPDVDESYPDTLVGAEIPEYIAREKADAYRTMMKPGELLITADTIVWLDGKVLGKPEGREGAIEMLRALSGKSHQVFTGVCLTTTEWQKSFTASSEVLFDVLSEDEILYYVDRYQPMDKAGAYGVQEWIGYIGVKSISGSFYNIMGLPIQKLYGELKKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QTMY01000016
EMBL· GenBank· DDBJ
RJU51296.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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