A0A3A5LQN3 · A0A3A5LQN3_STAAU

  • Protein
    3-dehydroquinate synthase
  • Gene
    aroB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 divalent metal cation per subunit. Can use either Co2+ or Zn2+.
NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site100-104NAD+ (UniProtKB | ChEBI)
Binding site124-125NAD+ (UniProtKB | ChEBI)
Binding site136NAD+ (UniProtKB | ChEBI)
Binding site145NAD+ (UniProtKB | ChEBI)
Binding site163-166NAD+ (UniProtKB | ChEBI)
Binding site178Zn2+ (UniProtKB | ChEBI)
Binding site242Zn2+ (UniProtKB | ChEBI)
Binding site256Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-dehydroquinate synthase activity
Molecular Functionmetal ion binding
Molecular Functionnucleotide binding
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-dehydroquinate synthase
  • EC number
  • Short names
    DHQS

Gene names

    • Name
      aroB
    • ORF names
      DQU50_03500
      , DQU51_15755
      , G6Y24_13150
      , GZ111_000905
      , M1K003_0309
      , SAMEA70153168_00398

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • M1K003
    • pt013
    • Pt013
    • pt014
    • Pt014
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Accessions

  • Primary accession
    A0A3A5LQN3
  • Secondary accessions
    • A0A4V1C9J9

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain62-3163-dehydroquinate synthase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    354
  • Mass (Da)
    40,237
  • Last updated
    2018-12-05 v1
  • Checksum
    59AB2D0C089B872D
MKLQTTYPSNNYPIFVEHGAIDHISTYIDQFDQSFILIDEHVNQYFADKFDDILSYENVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFVAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPTAVIYDLDFLKTLPFEQILSGYAEVYKHALLNGESTTQEIEQHFKDREILQSLNGMDKYIAKGIETKLDIVVADEKEQGVRKFLNLGHTFGHAVEYNHKIAHGHAVMIGIIYQFIVANILFNSNHDIQHYINYLTKLGYPLETITDIDFETIYQYMLSDKKNDKQGVQMVLIKHFGDIVVQHIDQTTLQHACEQLKTYFK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAIIGN010000001
EMBL· GenBank· DDBJ
CAC8215039.1
EMBL· GenBank· DDBJ
Genomic DNA
BDVT01000001
EMBL· GenBank· DDBJ
GBV19341.1
EMBL· GenBank· DDBJ
Genomic DNA
JAALTR010000315
EMBL· GenBank· DDBJ
NGW68405.1
EMBL· GenBank· DDBJ
Genomic DNA
QNXH01000001
EMBL· GenBank· DDBJ
TXL38908.1
EMBL· GenBank· DDBJ
Genomic DNA
QNXF01000002
EMBL· GenBank· DDBJ
TXL46896.1
EMBL· GenBank· DDBJ
Genomic DNA
CP152420
EMBL· GenBank· DDBJ
XAJ30604.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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