A0A395RG82 · A0A395RG82_9HYPO
- ProteinPeptidyl-prolyl cis-trans isomerase-like 2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids578 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
Catalytic activity
- [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | catalytic step 2 spliceosome | |
Molecular Function | peptidyl-prolyl cis-trans isomerase activity | |
Molecular Function | ubiquitin protein ligase activity | |
Biological Process | protein folding | |
Biological Process | protein peptidyl-prolyl isomerization | |
Biological Process | protein polyubiquitination |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptidyl-prolyl cis-trans isomerase-like 2
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium
Accessions
- Primary accessionA0A395RG82
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 40-114 | U-box | ||||
Sequence: RRLPFNFCAASLQPFKNPVCTPDGTIFDVEVIGAWLEKHPNQNPVTGESLQKKDLIRLNFARNSESDSLGAGLSD | ||||||
Region | 204-223 | Disordered | ||||
Sequence: TKEQEEERNAGNINSSALGS | ||||||
Domain | 328-475 | PPIase cyclophilin-type | ||||
Sequence: ETNLGDLTIELYPEFAPKAVWNFIRLCQTGYYKGVAFHRNIPNFMIQGGDPSGTGRGGQSIWGKYFDDEFDGPMSHNGRGTISMANKGKNTNSSQFFIAYKPTPHLDRKHTVFGKVVENLNVLSQMENVPTDGSNRPLNKIFIKDIVI | ||||||
Region | 505-529 | Disordered | ||||
Sequence: GTDDDKTTWTGKRIRSDGSMESTGV |
Sequence similarities
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length578
- Mass (Da)63,915
- Last updated2018-12-05 v1
- Checksum414B901417C09FC8
Keywords
- Technical term