A0A395LXV8 · A0A395LXV8_9BACT
- ProteinMultifunctional fusion protein
- GenefabZ
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids477 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
Catalytic activity
- a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O
Cofactor
Pathway
Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity | |
Molecular Function | metal ion binding | |
Molecular Function | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity | |
Molecular Function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | lipid A biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended name3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
- EC number
- Alternative names
- Recommended nameUDP-3-O-acyl-N-acetylglucosamine deacetylase
- EC number
- Short namesUDP-3-O-acyl-GlcNAc deacetylase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Chlorobiota > Chlorobiia > Chlorobiales > Candidatus Thermochlorobacteriaceae > Candidatus Thermochlorobacter
Accessions
- Primary accessionA0A395LXV8
Proteomes
Subcellular Location
Structure
Family & Domains
Sequence similarities
Belongs to the LpxC family.
Belongs to the thioester dehydratase family. FabZ subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length477
- Mass (Da)52,913
- Last updated2018-12-05 v1
- ChecksumD677200EEAA580B6