A0A395G9R5 · A0A395G9R5_9STAP

  • Protein
    NADPH-dependent 7-cyano-7-deazaguanine reductase
  • Gene
    queF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

tRNA modification; tRNA-queuosine biosynthesis.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site56Thioimide intermediate
Active site63Proton donor
Binding site78-80substrate
Binding site97-98substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionpreQ1 synthase activity
Biological Processqueuosine biosynthetic process
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADPH-dependent 7-cyano-7-deazaguanine reductase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine reductase
    • NADPH-dependent nitrile oxidoreductase
    • PreQ(0) reductase

Gene names

    • Name
      queF
    • ORF names
      BFS35_008540

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCM 4927
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Macrococcoides

Accessions

  • Primary accession
    A0A395G9R5

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    165
  • Mass (Da)
    19,446
  • Last updated
    2018-12-05 v1
  • Checksum
    C8D61F3648059A5F
MTGRQKEELQDITLLGNQNNKYLYEYDPSILESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFAAIYISYIPNIKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPGTKYEEIANYRLMNHDLYPETITNR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MJBI02000003
EMBL· GenBank· DDBJ
RAI80477.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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