A0A389MLR9 · A0A389MLR9_9HYPH
- ProteinBifunctional adenosylcobalamin biosynthesis protein
- GenecobU
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids173 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
Catalytic activity
- adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H+
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 13-20 | GTP (UniProtKB | ChEBI) | |||
Binding site | 38-40 | GTP (UniProtKB | ChEBI) | |||
Active site | 54 | GMP-histidine intermediate | |||
Binding site | 85 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | adenosylcobinamide kinase (ATP-specific) activity | |
Molecular Function | adenosylcobinamide kinase (GTP-specific) activity | |
Molecular Function | ATP binding | |
Molecular Function | cobinamide phosphate guanylyltransferase activity | |
Molecular Function | GTP binding | |
Biological Process | cobalamin biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional adenosylcobalamin biosynthesis protein
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Methylobacteriaceae > Methylobacterium
Accessions
- Primary accessionA0A389MLR9
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length173
- Mass (Da)18,654
- Last updated2018-12-05 v1
- MD5 ChecksumC385716AAF7520AEFC48CA7473FF8813
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BHEU01000006 EMBL· GenBank· DDBJ | GBU16756.1 EMBL· GenBank· DDBJ | Genomic DNA |