A0A388JUN4 · A0A388JUN4_CHABU

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.

Features

Showing features for binding site, active site, site.

112471002003004005006007008009001,0001,1001,200
Type
IDPosition(s)Description
Binding site558Mg2+ 1 (UniProtKB | ChEBI)
Active site630
Active site660Proton donor/acceptor
Binding site660Mg2+ 1 (UniProtKB | ChEBI)
Binding site662Mg2+ 1 (UniProtKB | ChEBI)
Site662Transition state stabilizer
Site719Important for catalytic activity
Binding site743Mg2+ 1 (UniProtKB | ChEBI)
Active site744Proton acceptor
Binding site744Mg2+ 1 (UniProtKB | ChEBI)
Site744Interaction with DNA substrate

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionmetal ion binding
Molecular Functionphosphoric diester hydrolase activity
Biological Processbase-excision repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Endonuclease/exonuclease/phosphatase domain-containing protein

Gene names

    • ORF names
      CBR_g21838

Organism names

Accessions

  • Primary accession
    A0A388JUN4

Proteomes

Genome annotation databases

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-20Disordered
Region267-386Disordered
Compositional bias271-288Polar residues
Compositional bias349-371Polar residues
Domain551-744Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,247
  • Mass (Da)
    142,096
  • Last updated
    2018-12-05 v1
  • Checksum
    8DBC1813AF879150
MAATPAQVASGRSPPPGLYEDRDYWEDEDRIRSLSALCFDDGVYPTEIDPGEMIVEGREVRFKLNTSPDDIEVKWLKKRTVTIIYRDAARFLSRKIKDDLVRAFEDGWVIGNEALLQNQRRGRIKIEGPGVASYVAKAKEVAEYMISEQSVEVNLGNESYRVQFKPWMTRAEFRELRKQEEDRVFWVMALQVPLDDMPFIYAQIEKAIGVAPVGPGLFNNQNLFEMSNFNGEQLAAWQGGTISADWLVANGIHPALWAGMLNPHGGVPARSQMGGNTQQPNSTAPGREGGQGMLNAEQPFGGGLRDGTDGGTPGPNENPEGSTSKPRGIGKQRRLSLTFVPGVTPEPSRASRLSRSGSEKSVSQEVGMVTPGQKTTRDRRLASTRDQSSKFPQFLVPLVCTAFRNSLWVVTWQKNLGPPLVFGQAVSEIPSTLDIERSLKNLYLDAIPMRVIPDVVMARILFGPTGSKVKYYVPLVDARLTEQKLSELKPHGLRLIPLATFAEAKKQELAKFMISPTMMTADALAELKMRLPKEKKLDSIFLKTTLTQSWPDIACLQETKLDNEKIGELGRWWDGPQIWYEAQETRGGVGILIHRDLAVQIVDYFADLWGRWVWVVLKSGDLIWAVVSVYAPVRRSERIAFWDELRVSLPDVDEVIIDGDWNTVLDSPPDQRGHGCAKDVLALVDLMLDLDLQDVYRTLRPAEPGYTWFSHRGKGRRLDYLLVGGGLKGQVINVEEVINPVSDHKPVIGQFNLAKEKPRGRGYFKLNTQNLHSEGLNKWTQGFWERWQKQKERFPTLADWWETGSRILSRLLDVFSRILALSRNKEERKCQKRVQDAEEKMKRHPISERAWGKERAKRLAEWDKKQQEKSELWAKRLKMKGLEVYDRMSRESFQKLTPARNGPALKELRHPFDPNEPVAVEPEELCRRQLKSEFWRAVLLAWRRVKPDIISAPCTKGEVLAQIIFENQNIRDNRGMMLMANSEPGSFGKAWVKRGVVRLRDLWNEFTGDWRSGEEMVGILRPGRYIRQRRQLVLDSIPKAWLQILSPAKPNPVGTWYEVEKERDPLAPQLREFVKLEEISEEGRRKFQRWQAQNGETNLSLCKEEEHCSLPGGPLVEIRVRETVSEEGDWKVKLWNVGAPLAVLKADPDQWAWRSRESRGEHVRLDEYTLELGYKVQEPHRTPLMTATQRWTRVLPDDSEKISNALQRCSQQLVESPFPRAATILWLASLLATPSTVEAKGRVLIEE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias271-288Polar residues
Compositional bias349-371Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BFEA01000020
EMBL· GenBank· DDBJ
GBG61495.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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