A0A384SY00 · A0A384SY00_9CAUD
- ProteinNAD--protein ADP-ribosyltransferase modB
- GenemodB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids202 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
ADP-ribosyltransferase that regulates transcription by ADP-ribosylation of host ribosomal protein S1. Additional identified targets include proteins involved in either translation or cellular metabolism such as elongation factor-Tu or trigger factor. Also reprograms the host's gene-expression system by RNAylating host ribosomal protein S1. ModB can attach NAD-capped RNAs to target proteins post-transcriptionally resulting in covalent RNA-protein conjugates.
Catalytic activity
- L-arginyl-[protein] + NAD+ = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H+
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | virion component | |
Molecular Function | NAD+-protein-arginine ADP-ribosyltransferase activity | |
Molecular Function | nucleotidyltransferase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD--protein ADP-ribosyltransferase modB
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageViruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Mosigvirus
Accessions
- Primary accessionA0A384SY00
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: This protein is injected from the virion into the bacterial cell.
Keywords
- Cellular component
Structure
Family & Domains
Sequence similarities
Belongs to the Tevenvirinae NAD--protein ADP-ribosyltransferase modA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length202
- Mass (Da)23,481
- Last updated2018-12-05 v1
- ChecksumC586BFC1B7E8413F