A0A384JRP0 · TREA_BOTFB

Function

function

Hydrolyzes intracellular trehalose to glucose (PubMed:16946258).
The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination (PubMed:16946258).
Regulates the level of trehalose as a protectant for cell integrity (PubMed:16946258).

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Pathway

Carbohydrate degradation.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site93Ca2+ (UniProtKB | ChEBI)
Binding site95Ca2+ (UniProtKB | ChEBI)
Binding site97Ca2+ (UniProtKB | ChEBI)
Binding site99Ca2+ (UniProtKB | ChEBI)
Binding site104Ca2+ (UniProtKB | ChEBI)
Binding site280substrate
Binding site287-288substrate
Binding site324substrate
Binding site333-335substrate
Binding site400substrate
Binding site449substrate
Binding site452substrate
Active site454Proton donor/acceptor
Active site658Proton donor/acceptor

GO annotations

AspectTerm
Cellular Componentalpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
Molecular Functionalpha,alpha-trehalase activity
Molecular Functioncalcium ion binding
Biological Processascospore formation
Biological Processtrehalose catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytosolic neutral trehalase
  • EC number
  • Alternative names
    • Alpha,alpha-trehalase
    • Alpha,alpha-trehalose glucohydrolase
    • Bctre1

Gene names

    • Name
      TRE1
    • ORF names
      BCIN_09g01310

Organism names

Accessions

  • Primary accession
    A0A384JRP0

Proteomes

Organism-specific databases

Subcellular Location

Phenotypes & Variants

Disruption phenotype

Increases cellular trehalose levels (PubMed:16946258).
Decreases conidial germination frequency (PubMed:16946258).
Resistance to thermal stress (PubMed:16946258).

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004528011-727Cytosolic neutral trehalase

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region47-72Disordered

Sequence similarities

Belongs to the glycosyl hydrolase 37 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    727
  • Mass (Da)
    83,085
  • Last updated
    2018-11-07 v1
  • Checksum
    DB3F46A4F84C92B8
MTSPLRKHRTSSVSSEIDPFAAAHVYYSNDTNQKSFRQARTRTYSSNQGIFSTPISGLEKPKRRGSHDDIGDHGRKFLIQVDSTLEALRKQEDTDDNHQITIEDVGPKSLPLGTATSNGFRRYDIRGTYMLSNLLQELTLAKENGREQIILDESRLNENPVNRLSRLIQGSFWDGLTRRIDGSVIEIAGRDPKDWTDDPRPRIYIPRGAPEQHAYYTKVATDRPEVRLDVCWLPEKITPEVVRDMNSKPGLLAVAMEEVIDPSTGEKTLKGLPFVVPGGRFNELYGWDSYMESLGLIVNDKVHLAKSMVQNFCFCIEHYGKILNATRSYYLCRSQPPFLTDMALRVFDKIKHEPGSLDFLKTAILAAIKEYHSVWTAEPRYDPVTGLSRYRPEGLGVPPETEASHFEHLLAPYAEKYNMTFKEFVDAYNNGRVVEKELDDYFLHDRAVRESGHDTSYRLERVCADLATIDLNSLLYKYEKDIAYTIRTFFQDKLEVPAEFCVGDMTPGQLQTSSMWDRRARGRKLAIDKYLWNKEKGMYFDYNTLKKEQCTYESATTFWAMWAGVASPQQAASLVTNALPKFEAAGGLLSGTEESRGAVGLDRPNRQWDYPYGWAPQQMLAWTGLLRYNYQEDAERLAYKWLFMITTAFVDFNGVVVEKYDVTRVVDPHKVDAEYGNQGSDFKGVAKEGFGWVNASYVYGLQIINAHMRRTLGTLTPWDQYNKAMNL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP009813
EMBL· GenBank· DDBJ
ATZ53256.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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