A0A384JK99 · PTF_BOTFB

Function

function

Prenyltransferase that attaches isoprenoid moieties to carbon atoms of aromatic substrates in an enzyme-catalyzed Friedel-Crafts reaction (PubMed:20351110).
Shows specificity for dimethylallyl diphosphate (DMAPP) and does not accept geranyl diphosphate (GPP) or isopentenyl diphosphate (IPP) (PubMed:20351110).
Prenylates the artificial substrate 2,7-dihydroxynaphthalene (2,7-DHN), as well as dihydrophenazine-1-carboxylic acid and 4-hydroxybenzoic acid at lower levels (PubMed:20351110).
Only traces of products are detected with aspulvinone E or flaviolin as substrates; and no product is formed with L-tryptophan, L-tyrosine, or 4-hydroxyphenylpyruvate (PubMed:20351110).
Ptf seems no to be involved in the prenylation reaction in the biosynthesis of aspulvinone H and J and the physiological function of ptf remains unknown (PubMed:20351110).

Miscellaneous

The gene is not located within a recognizable secondary metabolic gene cluster.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
1010 μMDMAPP
996 μM2,7-dihydroxynaphthalene

GO annotations

AspectTerm
Molecular Functionprenyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aromatic prenyltransferase
  • EC number

Gene names

    • Name
      ptf
    • ORF names
      BCIN_06g02600

Organism names

Accessions

  • Primary accession
    A0A384JK99

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004554621-309Aromatic prenyltransferase

Family & Domains

Sequence similarities

Belongs to the aromatic prenyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    309
  • Mass (Da)
    34,474
  • Last updated
    2018-11-07 v1
  • Checksum
    434F9267B029F90A
MVVQAVSESLKFDQSRFLNDIQILSAAINAPYSESTTKKVLSVFSDSFHDGVVLWRATDRVGDALNYRFYSRRPIDTVTIASSAGLLSPDVVSNLGRLVTSWSSLYDGLPEESCDFDAEKGLVKAWVYMRGMRPLGDILSAEGVPESLKQHEERFKALELEKVRHVAVDYQKATVNLYFRAQGPISLQQATSFNALAGAGPPSQTQFLEMQEFLNAVGYTFAVTIRVDSGDIERVGYYALKLPDRATKNWPVINAQLEKFAQFAPSYDREEMNAVAWSFGGTKRYVKFERSYCGELVPLIKGWGTTLSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP009810
EMBL· GenBank· DDBJ
ATZ50774.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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