A0A381NGK5 · A0A381NGK5_9ZZZZ
- ProteinFO synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids829 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
Catalytic activity
- 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 5'-deoxyadenosine + L-methionine + NH4+ + H+
Cofactor
Pathway
Cofactor biosynthesis; coenzyme F0 biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity | |
Molecular Function | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFO synthase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageunclassified sequences > metagenomes > ecological metagenomes
Accessions
- Primary accessionA0A381NGK5
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 42-289 | Radical SAM core | |||
Domain | 460-699 | Radical SAM core | |||
Region | 786-829 | Disordered | |||
Sequence similarities
In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
In the N-terminal section; belongs to the radical SAM superfamily. CofG family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length829
- Mass (Da)90,388
- Last updated2018-11-07 v1
- ChecksumD41E5B284C8FB534
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
UINC01000305 EMBL· GenBank· DDBJ | SUZ52958.1 EMBL· GenBank· DDBJ | Genomic DNA |