A0A380MUZ8 · A0A380MUZ8_9GAMM

  • Protein
    Multifunctional fusion protein
  • Gene
    msrAB_1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site261
Active site556Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrAB_1
    • Synonyms
      msrA
      , msrB
    • ORF names
      NCTC10717_00990

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCTC10717
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Cardiobacteriales > Cardiobacteriaceae > Suttonella

Accessions

  • Primary accession
    A0A380MUZ8

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region46-66Disordered
Domain72-216Thioredoxin
Domain444-567MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    588
  • Mass (Da)
    64,393
  • Last updated
    2018-11-07 v1
  • Checksum
    803D541A6655F361
MNTPIKHTMSHIMNHVTKNHAAKGSIALISVLLSACGQMSNAHDNVTNGDAVTHSDMAGKTDSKDMLPSKTLKNLSALPQITAHLGETGKQVIDADKPTLVKFWASWCPLCLGTLAETQDWRQDPAFAGLNIITVASPSHLNEKPADEFRQWYAGVQGDYPKLPVLLDDSGELIARLGVQVYPSWAILDKKGNLVRLIKGNLTTEQAQALAANADKDFADLKGKNTPSVVANAKPVSSAKAFYKADGSPIRTKTIYLAGGCFWGVEAYMERIDGVVDAVSGYANGNTDNPSYEQVIAGSGHAETVKVTYDSDKIDLATLLAYYFRVIDPTSVNKQGNDRGVQYRTGIYYPKDSTVEDKAVITNALAQLQNKHKSSIVVENLPLRNFTQAEDYHQDYLSKNPNGYCHIDISLADDALPTEPSQSLAPANSIEQALDPKRYQTYKDKNLKNTLSKAQYNITQNGGTERAFSHEYDHLFAPGIYVDVVSGEPLFLSTDKYNSGCGWPSFTKPIAPQVITQHNDTSYNMIRTEVRSRVADSHLGHVFPDGPKDKGGLRYCINGGALQFIPVDKMQQSGYGVFVPKIKMNNEN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UHIA01000004
EMBL· GenBank· DDBJ
SUO96410.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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