A0A380G8G4 · A0A380G8G4_STAIN

Function

function

Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.

Features

Showing features for binding site, active site.

125320406080100120140160180200220240
Type
IDPosition(s)Description
Binding site9-11substrate
Active site97Electrophile
Active site169Proton acceptor
Binding site175substrate
Binding site215substrate
Binding site236-237substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
    ; TPI
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      tpiA
    • ORF names
      NCTC11048_02520

Organism names

  • Taxonomic identifier
  • Strain
    • NCTC 11048
  • Taxonomic lineage
    Bacteria > Bacillati > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus > Staphylococcus intermedius group

Accessions

  • Primary accession
    A0A380G8G4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    253
  • Mass (Da)
    27,347
  • Last updated
    2018-11-07 v1
  • MD5 Checksum
    6E50A31FFBC65A124DBEE33C72BEF517
MRKPIIAGNWKMNKTVQEAKDFVQALPALPDTNEVEAVICAPTIQLDALISLTKENVAPGLKIGAQNTYFEDSGAFTGETSPVALEALGVSYVVIGHSERRDLFHETDEDINKKAHAVFNHNMTPIICVGESDEERESGKANEIVEAQVEKALKGLSDEQIKQVVIAYEPIWAIGTGKSSTAKDANEMCAAVRQKIAQLTSDEVAQATRIQYGGSVKPNNIKEYMAETDIDGALVGGASLKVEDFTQLLEGAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UHDP01000003
EMBL· GenBank· DDBJ
SUM47439.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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