A0A379SU95 · A0A379SU95_SALER
- ProteinPTS system mannose-specific EIIAB component
- GeneptsL_1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids298 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.
Catalytic activity
- D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 10 | Tele-phosphohistidine intermediate; for EIIA activity | |||
Active site | 173 | Pros-phosphohistidine intermediate; for EIIB activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | kinase activity | |
Molecular Function | protein-N(PI)-phosphohistidine-sugar phosphotransferase activity | |
Biological Process | phosphoenolpyruvate-dependent sugar phosphotransferase system | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePTS system mannose-specific EIIAB component
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A379SU95
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 10 | Phosphohistidine; by HPr | |||
Modified residue | 55 | N6-acetyllysine | |||
Modified residue | 173 | Phosphohistidine; by EIIA | |||
Modified residue | 232 | N6-acetyllysine | |||
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length298
- Mass (Da)32,177
- Last updated2018-11-07 v1
- MD5 ChecksumD60E7A6B671B4CE9E47CC9D2EE752140
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
UGXD01000002 EMBL· GenBank· DDBJ | SUG32967.1 EMBL· GenBank· DDBJ | Genomic DNA |