A0A371BTA0 · A0A371BTA0_9MICC

  • Protein
    Glycine dehydrogenase (decarboxylating)
  • Gene
    gcvP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentglycine cleavage complex
Molecular Functionglycine binding
Molecular Functionglycine dehydrogenase (decarboxylating) activity
Molecular Functionpyridoxal phosphate binding
Biological Processglycine decarboxylation via glycine cleavage system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycine dehydrogenase (decarboxylating)
  • EC number
  • Alternative names
    • Glycine cleavage system P-protein
    • Glycine decarboxylase
    • Glycine dehydrogenase (aminomethyl-transferring)

Gene names

    • Name
      gcvP
    • ORF names
      DXK94_05610

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • RT-1
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Micrococcaceae > Arthrobacter

Accessions

  • Primary accession
    A0A371BTA0

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue708N6-(pyridoxal phosphate)lysine

Interaction

Subunit

The glycine cleavage system is composed of four proteins: P, T, L and H.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-450Glycine cleavage system P-protein N-terminal
Domain479-737Glycine cleavage system P-protein N-terminal
Domain778-899Glycine dehydrogenase C-terminal

Sequence similarities

Belongs to the GcvP family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    958
  • Mass (Da)
    101,456
  • Last updated
    2018-11-07 v1
  • Checksum
    F3708378B613AD86
MEFLVTVSPASASLASAATFVDRHIGARRQADVDAMLKAVGFDTVDALVDTAVPKDIRQETPLKLSAALSEVEALAELRKLAAKNRTAVQMIGQGYFDTVTPPVIRRNILESPAWYTAYTPYQPEISQGRLEALLNFQTMVQDLVGLPIANASLLDEATAVAEAVLMMRRANKNKDARDGKTVLDADCLPQTIAIVKGRAEALGFEVEIADLSAGLPDGAINGVVLQQPGVSGRVFDHSAVIAEAKERGALVTVAADLLALTLITPPGEQGADIAVGSAQRFGVPLFFGGPHAAYMAVQKGLERSMPGRLVGVSKDDAGVPAYRLALQTREQHIRREKATSNICTAQALLAIVASMYAVYHGPEGLKAIAQTANRHARTLAASLKAAGAEVLHTSFFDTVTVRVPGRAAEIVAAAEAKGINLRGIDADTVGISVDETTTTAVVADVVSVFGAEAVGSTGSFALDPAVERSSGYLQHPVFNTHRSETQLLRYIRKLSDRDLALDRTMIPLGSCTMKLNATAEMEAISWPEFASIHPFAPDSQTEGWRELIADLEAQLTEITGYDQVSIQPNAGSQGELAGLLAIRGYHLSRGDEQRNVCLIPASAHGTNAASAVLAGMKVVVVATAADGTIDHADLYAKIDAHKDALSAIMITYPSTHGVYDADVREVCDAIHAAGGQVYIDGANLNALVGLAQPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVAAKAHLAPFMPGDAASWTEGNDVPISASRFGSAGVLPISWAYVKLMGGEGLTEATKSALLAANYIASRLNEHFPVLYTGEGGLVAHECILDLRELTAKTGVTAEDVAKRLIDFGFHAPTLAFPVAGTLMVEPTESEDLAEMDRFIEAMITIRHEIDQVANGDFTVADSPLRRAPHTAAAVVSSDWDRAYPREQAAFPVHHLKQDKYFPPVGRIDGAAGDRNLICSCPPLEDFEN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QRGQ01000005
EMBL· GenBank· DDBJ
RDV11149.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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