A0A371BKP4 · A0A371BKP4_9MICC

  • Protein
    Adenosine 5'-phosphosulfate reductase
  • Gene
    cysH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site113[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site114[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site196[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site199[4Fe-4S] cluster (UniProtKB | ChEBI)
Active site222Nucleophile; cysteine thiosulfonate intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionadenylyl-sulfate reductase (thioredoxin) activity
Molecular Functionmetal ion binding
Molecular Functionphosphoadenylyl-sulfate reductase (thioredoxin) activity
Biological Processsulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosine 5'-phosphosulfate reductase
  • EC number
  • Short names
    APS reductase
  • Alternative names
    • 5'-adenylylsulfate reductase
    • Thioredoxin-dependent 5'-adenylylsulfate reductase

Gene names

    • Name
      cysH
    • ORF names
      DXK94_20550

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • RT-1
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Micrococcaceae > Arthrobacter

Accessions

  • Primary accession
    A0A371BKP4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain33-202Phosphoadenosine phosphosulphate reductase

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    226
  • Mass (Da)
    24,677
  • Last updated
    2018-11-07 v1
  • Checksum
    D96357EA82275DED
MKALAEAGAAELGWDAPARDVIAWVERNFDLPAVAVACSMADAVLPALVADQMPGVDVLFLETGYHFPETYATRDEVAANLRVNVVDVLPENTVEQQDRLLGKNLFARDAAQCCALRKVAPLRRTLSGYELWFTGVRRDEAPTRTNTPLVTWDEANGLVKVNPVAAWTFDQLVQYSDDNLLPVNPLLSQGYPSIGCQPCTRKVAPGDDPRAGRWAGTDKTECGLHV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QRGQ01000050
EMBL· GenBank· DDBJ
RDV08138.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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